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Articaine v lidocaine for third molar removal

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This review comparing the effectiveness of articaine and lidocaine for lower third molar surgery included 14 RCTs. The findings suggest that articaine is superior to lidocaine for use in lower third molar however the available are small so additional larger high quality studies would be helpful to strengthen the evidence.

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Compassion-focused therapy for psychosis: study suggests it’s feasible and acceptable, so what next?

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Ellen Iredale and Poppy Brown summarise a case-series study on compassionā€focused therapy for distressing hallucinations and delusions in psychosis, suggesting the potential to benefit people with psychosis.

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Individual, group and guided self-help CBT for panic disorder: most delivery formats equally effective, but more evidence needed

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Hannah Wallace summarises a network meta-analysis comparing four different formats of CBT for panic disorder, which finds “no efficacy differences between CBT delivered as guided self-help, or in the face-to-face individual or group format in the treatment of panic disorder”.

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Antimicrobial photodynamic therapy and bacterial load in endodontics

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This review of the efficacy of adjunctive photodynamic therapy (aPDT) on reducing bacterial load in the primary endodontic treatment of teeth with chronic apical periodontitis included 8 studies. While the findings suggest a benefit from aPDT the limited number and quality of the availabel studies mean the findings should be interpreted cautiously.

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Curcumin for treatment of oral submucous fibrosis

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This review of the efficacy of curcumin in improving symptoms in patients with oral submucous fibrosis (OSF) included 13 RCTs. The main findings suggest no significant difference between curcumin and controls although the studies are small and heterogenous.

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What’s the relationship between the menstrual cycle and suicidal ideation?

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Gemma Sawyer discusses new research on the menstrual cycle as a possible acute trigger for suicidal ideation.

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Articaine-adverse effects in paediatric dental patients

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This review of the effects and adverse reactions between articaine and lidocaine in paediatric dental procedures included 8 RCTS. Three of the included studies were at high risk of bias 2 at low risk and 3 at unclear risk. The findings suggested no difference in adverse effects between the two anaesthetics with the certainty of evidence being assessed as moderate.

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The experience of treatment-resistant depression: we need to rethink treatment for people who do not respond to antidepressants

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Amelia Talbot summarises a qualitative meta-synthesis exploring people’s experiences of living with ‘treatment-resistant’ depression.

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What crisis and acute mental health care is available to those with a ‘personality disorder’ diagnosis?

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Keir Harding finds little published evidence to support people with ‘personality disorder’ diagnoses when they are in crisis.

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Self-adhesive flowable composite resins v flowable composite resin for occlusal cavities in permanent teeth

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This review of the clinical performance of self-adhesive flowable composites and flowable composites for occlusal cavities in permanent teeth included 5 RCTs. . While the review found no significant differences between SAFCs and FCs in terms of retention, secondary caries, marginal discoloration, and postoperative sensitivity outcomes the limited number and quality of the small number of available studies mean the findings should be viewed cautiously.

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