comorbidity

shutterstock_135966185

Introduction

Comorbidity, or the co-occurrence of two distinct medical conditions, is a common phrase in both physical and mental health. Whilst the term was originally conceived to describe medical phenomena, the term was adopted by psychiatry in the description of more than one clinical presentation occurring simultaneously. However, its use in psychiatry is not without controversy. 

What we know already

Large-scale prevalence data can seemingly tell us much about the high rate of comorbidity in mental health. Data from US National Comorbidity Survey, for example, suggested that, of those reporting mental health difficulties (across a 12-month prevalence), only 55% carried a single psychiatric diagnosis.

One important area of recent research concerns the rates of comorbidity of physical and mental health difficulties, particularly in the area of chronic health conditions. Mental Elf blogs have reported that people with schizophrenia are significantly more likely to die from heart disease and cancer; while the National Schizophrenia Audit calls for improved monitoring of physical health in people with schizophrenia. We know that depression and anxiety are more common when a person has a chronic health problem, and this comorbidity leads to poorer clinical and quality of life outcomes. This has led to an increase in interventions targeting the psychological consequences of chronic ill health.

Areas of uncertainty

The controversy in psychiatric comorbidity is the issues of mutual exclusivity. We are not able to conclude as to whether ‘comorbid’ psychiatric diagnoses are separate clinical entities, or multiple features of the same underlying cause. This has led to much criticism of the term ‘psychiatric comorbidity’.

Furthermore, certain diagnostic labels, such as personality disorders, attract particular scrutiny, due to their high levels of comorbidity with other mental health diagnoses. Similarly, people often meet the criteria for more than one personality disorder. This again creates uncertainty as to the precise nature of the condition, or conditions, being diagnosed.

What’s in the pipeline?

The recent publication of the Diagnostic and Statistic Manual (DSM)-5 seemingly retains the notion that multiple distinct clinical diagnoses exist, thus maintaining the argument for psychiatric comorbidity. Alternative conceptualisations have been suggested, along dimensional models, such as ‘anxious-misery’, ‘externalising’ and ‘fear-based’ dimensions. However, these were not adopted in the DSM-5.

As our understanding of mental health conditions continues to improve, so too hopefully will our understanding of comorbidity, and its relevance to psychological and psychiatric phenomena.

References

First, M. B. (2005). Mutually exclusive versus co-occurring diagnostic categories: the challenge of diagnostic comorbidity. Psychopathology, 38, 206-210. [Abstract]

Kessler, R. C., Chiu, W. T., Demler, O., & Walters, E. E. (2005). Prevalence, severity, and comorbidity of 12-month DSM-IV disorders in the National Comorbidity Survey Replication. Archives of general psychiatry, 62, 617-627. [Abstract]

Naylor, C., Parsonage, M., McDaid, D., Knapp, M., Fossey, M. and Galea, A. (2012) Long-term conditions and mental health: the cost of co-morbidities. The King’s Fund, London, UK. [Full text]

Acknowledgement

Written by: Patrick Kennedy-Williams
Reviewed by:
Last updated: Sep 2015
Review due: Sep 2016

Our comorbidity Blogs

The caring dyad: how patients and their informal carers experience severe mental illness and cardiometabolic disease

marc-najera-SwK6MSxTLDE-unsplash

Lydia Poole considers the caring dyad (the relationship experience of the patient and their informal carer) and the realities of living with cardiometabolic risk, metabolic syndrome and severe mental illness.

[read the full story...]

ICU survivors at increased risk of suicide and self-harm after discharge

Hands holding yellow gold ribbon over blue sky, Sarcoma Awareness, Bone cancer, childhood cancer awareness, September yellow, World Suicide Prevention Day, endometriosis day concept

Charlotte Huggett reviews a recent Canadian population-based cohort study, which examines rates of suicide and self-harm in adult survivors of critical illness.

[read the full story...]

A long-term physical health condition changes everything: therapeutic responses to psychological distress must change too #BABCP2022

Open,Wooden,Door,To,The,New,World,With,Green,Environment.

Dona Matthews reviews a paper on an evidence-based theory of psychological adjustment to long-term physical health conditions and applications in clinical practice, which will be presented at the #BABCP2022 conference in London later this week.

[read the full story...]

HIV stigma and depression: new systematic review of people in South Africa

LANGA TOWNSHIP, SOUTH AFRICA - JULY 12, 2015 - A young girl poses for a photograph at her home in Langa, South Africa, a township located on the outskirts of Cape Town.

Rudo Dude summarises a systematic review which examines the links between HIV stigma and depression among people living with HIV/AIDS in South Africa.

[read the full story...]

How to improve oral health in people with severe mental illness #MindYourSmile

Start tweeting your ideas to #MindYourSmile now!

Easter Joury summarises a recent systematic review on improving oral health in people with severe mental illness.

We are having a tweet chat at 8-9pm BST on Monday 11th July to discuss how best to support oral health in people with severe mental illness. You can join in by following the #MindYourSmile hashtag on Twitter.

[read the full story...]

Indigenous people living with psychosis in Australia: a novel example of clinical research and implications for population health

david-clode-LanGUEBuDPY-unsplash

Shuichi Suetani and Leshay Chong summarise a study exploring multimorbidity and vulnerability among those living with psychosis in Indigenous populations in Australia.

[read the full story...]

Choosing between antipsychotics to reduce the risk of breast cancer in women with schizophrenia

angiola-harry-nJv6xnlpNaA-unsplash

Peter Knapp and Suzy Ker review a recent study from Finland, which suggests that women with schizophrenia who take prolactin-increasing antipsychotics for at least five years, have an increased risk of developing breast cancer.

[read the full story...]

Misdiagnosis or missed diagnosis? What are the potential implications for undiagnosed autistic people?

Headshot,Of,A,Young,Man,Looking,Sad,At,The,Window

Rachel Symons reviews a recent Italian study which finds that autism spectrum disorder is still commonly undiagnosed and misdiagnosed in adults.

[read the full story...]

One size doesn’t fit all: new insights into eating disorders and autism

Portrait,Of,A,Beautiful,Natural,Looking,Young,Woman,With,No

In her debut blog, Shania Lorenz summarises a qualitative research study that looks at the experiences of women with eating disorders and autism, their parents and health professionals.

[read the full story...]

Living with mental health problems during COVID-19: how does it feel?

press-features-S_8rGErVlH4-unsplash

In her debut blog, Anjana Greedharee reviews a co-produced, participatory qualitative study on the experiences of living with mental health problems 
during the COVID-19 pandemic in the UK.

[read the full story...]