Oral mucositis: Risk factors in paediatric oncology patients

The authors suggest a number of factors that may lead to increased prevalence, including depression, childhood trauma, low self-esteem and genetic risk.

Manas Dave takes a look at this review aiming to identify the potential risk factors associated with the development of oral mucositis in paediatric patients. While a range of risk factos are higlighted it is worth noting that 80-100% of all children having chemotherapy experience some degree of mucositis.

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Can psilocybin-assisted psychotherapy relieve existential crises in cancer patients?

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Pascal Immanuel Michael reviews a randomised controlled trial examining long-term outcomes of psilocybin-assisted psychotherapy for existential distress in patients with cancer.

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Is there a causal link between mental health problems and risk of COVID-19 infection?

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In his debut blog, Andrew Steptoe summarises two recent papers using electronic health record datasets, which suggest that having a psychiatric diagnosis may put people at risk of COVID-19 infection.

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Metastasis to the oral and maxillofacial region

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This review of metastasis to the oral and maxillofacial region included 217 studies (190 case reports,24 case series ). Metastasis were uncommon, but identified from 29 primary sites, the most common sites being lung the lungs (20.97%), breast (12.06%) and kidney (11.78%).

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Weekly singing in choir may improve the mental health of cancer carers

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Katherine Tallent writes her debut blog on a recent longitudinal controlled study exploring psychosocial singing interventions for the mental health and well-being of family carers of patients with cancer.

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Cancer screening disparities in people with mental illness

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Emily Peckham from the Closing The Gap Network writes her debut blog on a new systematic review, which finds that people with mental illnesses were less likely to receive screening for cancer compared to the general population.

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Oral Cancer: Elective neck dissection or watch and wait?

Bariatric surgery and marked weight loss is likely to improve knee complaints but there is a need for high quality studies

There is an ongoing debate about the management of patients with oral cavity squamous cell carcinoma and clinically negative cervical lymph nodes. Some clinicians favour preventive elective neck dissection (END) which although is linked with favourable survival has an adverse effect on quality of life while others adopt a wait and watch policy. The aim [read the full story…]

Oral mucositis in cancer patients: the effect of oral supplementation

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This review of of the effects of oral supplementation on the prevention and/or treatment of oral mucositis in patients with cancer undergoing chemotherapy and/or radiotherapy included 12 RCTs and suggest that Zinc supplements may be beneficial.

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Mucositis in adult cancer patients reduced with keratinocyte growth factor

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This Cochrane review of cytokines and growth factors for preventing oral mucositis in patients having cancer treatment included 35 RCTs finding keratinocyte growth factor beneficial in the prevention of oral mucositis .

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Oral mucositis in cancer patients: no benefit from chlorhexidine mouthwash

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This review of chlorhexidine (CHX) for prevention & treatment of oral mucositis included 12 RCTs with 9 contribution to the meta-analysis. CHX was not significantly effective in preventing mucositis or reducing its severity.

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