Why do people who were maltreated as children face higher risks of both mental and physical illness? A new Mendelian randomisation study suggests that metabolic markers — like triglycerides and blood sugar — may be part of the chain connecting adversity to later multimorbidity.
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Psychiatric disorders are highly heritable, but are the genes we identify in GWAS the same ones our medications target? This new study digs into the overlap and raises questions about how we develop treatments.
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A massive new multi-ancestry genetic study of bipolar disorder has uncovered hundreds of risk loci and highlighted biological pathways that may guide more precise treatments and prevention strategies in the future.
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Nick Donnelly discusses how one’s genetic predisposition to shorter sleep is associated with the onset of depression in older adults.
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Ed Palmer considers new research on the genetic risk for Tourette Syndrome and it’s relationship to other mental and physical health conditions.
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