Results: 606

For: randomised controlled trial

Inferior alveolar nerve block 2% mepivacaine versus 4% articaine – trial

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This well conducted randomised controlled trial assessed inferior alveolar nerve block (IANB) success of 2% mepivacaine and 4% articaine in patients with symptomatic irreversible pulpitis (SIP) in mandibular molars during access cavity preparation and instrumentation.

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Acceptance and commitment therapy for early psychosis: results from the INTERACT trial

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Silke Vereeken summarises the INTERACT randomised controlled trial, which reports on the efficacy of Acceptance and Commitment Therapy in daily life for people with early psychosis.

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Intensive home treatment in crisis: a randomised controlled trial from the Netherlands

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Lucy Maconick and Sonia Johnson appraise a recent trial conducted in Amsterdam, which finds that intensive home treatment substantially reduces the use of hospital beds in acute psychiatry, without compromising patient safety.

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Peer support does not reduce hospital readmissions: the final word?

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Danielle Lamb reviews a recent large randomised controlled trial on peer support for discharge from inpatient mental health care versus care as usual in England (the ENRICH study).

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Psychiatric Advance Directives: more effective when facilitated by peer workers, according to French RCT

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Rob Allison considers a French randomised controlled trial, which provides support for the use of peer worker–facilitated psychiatric advance directives to prevent compulsory rehospitalisation in people with severe mental illness.

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Clinician-supported computerised CBT effective in US primary care, but what about digital exclusion?

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In her debut blog, Sue Brown explores an RCT from the US, which finds that computerised CBT was effective at treating depression in primary care patients, and was also beneficial to those with lower educational attainment, reading proficiency and incomes.

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Aerobic exercise for major depression: the role of reward processing and cognitive control

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Francesca Bentivegna summarises a trial which looks at how aerobic exercise can help students with major depression by examining reward and cognitive control as predictors and treatment targets.

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E-cigarettes vs nicotine patches: are either adequate to support pregnant smokers?

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In her debut blog, Tuba Saygın Avşar summarises a recent RCT, which finds that “E-cigarettes might help women who are pregnant to stop smoking, and their safety for use in pregnancy is similar to that of nicotine patches.”

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Deep brain stimulation may improve long-term quality of life for people with ‘treatment-resistant depression’

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Alex Pike and Jonathan Roiser appraise and summarise a recently study in the Brain Stimulation journal, which looks at the long-term efficacy and quality of life of deep brain stimulation for severe depression.

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Can brief social contact videos reduce transphobia and increase treatment-seeking among adolescents?

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Talen Wright critically reviews a randomised controlled trial evaluating the effectiveness of brief social contact video on transphobia and depression-related stigma among adolescents.

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