Results: 675

For: randomised controlled trial

Could CBT be a feasible treatment for Depersonalisation-Derealisation Disorder?

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DDD affects around 2% of people but has no approved treatment. A new feasibility trial asks whether CBT-f-DDD could change that.

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Culturally inclusive parenting programme benefits families in deprived urban areas

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This RCT of 674 diverse, disadvantaged parents found that Strengthening Families, Strengthening Communities (SFSC) group parenting support improved wellbeing and parent-child relationships at modest cost.

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Oxytocin and affection: does intimacy help wounds heal faster?

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Oxytocin alone didn’t speed wound healing in couples, but combined with affectionate touch and partner appreciation, it showed modest benefits. Social context matters more than hormones.

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Vitamin C, gut bacteria, and mental vitality: early findings

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In this small RCT, vitamin C supplementation improved attention and work absorption in healthy young adults with low vitamin C levels, alongside changes in gut bacteria and inflammation markers.

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From panic to progress? Focused CBT may help for panic disorder, but bigger trials needed

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This small trial suggests Psychological Wellbeing Practitioners might deliver focused panic therapy effectively. But with only 46 participants included in the final analysis, larger trials are needed to confirm.

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Do antipsychotics slow down thinking? New evidence from healthy volunteers

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New research reveals how antipsychotic medications affect working memory speed in healthy adults, providing crucial insights into the cognitive side effects of these widely prescribed drugs.

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Does the flu shot make you feel sick? What this randomised trial tells us about vaccine-induced inflammation

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Although a flu vaccine activated the immune system and raised cytokine levels in this randomised trial, participants didn’t feel substantially different from the placebo group. Vaccine models can help study subtle inflammation effects.

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Healing takes time: Can cognitive therapy for PTSD help young people in CAMHS? Insights from DECRYPT

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PTSD in young people is common, complex, and often entangled with depression, anxiety, and multiple traumatic experiences. A major new UK trial (DECRYPT) tested whether a structured form of trauma-focused cognitive therapy (CT-PTSD) can work in real CAMHS settings for those with the most severe difficulties.

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Targeting distressing mental imagery in psychosis: a neglected but promising area for intervention

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What if therapy focused not on thoughts or voices, but on the vivid images that often accompany them? The iMAPS-2 trial tested a novel imagery-focused therapy for psychosis, showing it’s safe, acceptable, and ready for a full-scale trial.

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Silencing the voices? Landmark German study finds rTMS modestly effective for auditory hallucinations

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A large multicentre trial from Germany found that repetitive Transcranial Magnetic Stimulation (rTMS) significantly reduced auditory hallucinations compared to sham treatment. Could this safe and well-tolerated therapy finally offer new hope for people with persistent voices?

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