Risk factors and peripheral biomarkers for schizophrenia spectrum disorders

This 'umbrella review' aimed to systematically appraise the meta-analyses of observational studies on risk factors and peripheral biomarkers for schizophrenia spectrum disorders.

Marcus Munafo considers the findings of a systematic review of meta-analyses of observational studies, which looks at risk factors and peripheral biomarkers for psychotic disorders on the schizophrenia spectrum.

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The Origins of Happiness: can we predict life satisfaction?


Paul Ramchandani considers the methods, findings and implications of a new book by Andrew E. Clark, Sarah Fleche, Richard Layard, Nattavudh Powdthavee and George Ward, entitled: ‘The Origins of Happiness: The science of well-being over the life course’.

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Should people with schizophrenia be offered depot antipsychotics as first line treatment?


Murtada Alsaif reports on a new nationwide Swedish cohort study that explores the real-world effectiveness of oral and depot antipsychotics for people with schizophrenia.

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“Won’t you be my neighbour?” Psychosis and violent reoffending: does where you live matter?


Derek Tracy and Krisna Patel consider neighbourhood influences on violent reoffending risk in released prisoners diagnosed with psychotic disorders.

The blog also features a half hour audio podcast with the lead researcher Amir Sariaslan, the blogger Derek Tracy and Chief Elf André Tomlin.

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Antipsychotic efficacy measured by real-world observational study


Tracey Roberts examines whether a retrospective observational study accurately investigates the effectiveness of second and first generation antipsychotics.

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Locked wards vs open wards: does control = safety?


André Tomlin summarises a 15 year observational study published today in The Lancet Psychiatry, which provides fascinating insight into suicide risk and absconding in psychiatric inpatient units with locked wards and open door policies.

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The moral and emotional labour of care workers in residential homes


Jill Manthorpe discusses a case study on how the emotional and moral labour of care workers operates in residential settings.

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Mood Matters: mood instability is common and associated with poor outcomes


Farhana Mann summarises an observational study of mood instability in people with mental illness, which explores its relationship with days spent in hospital, frequency of admissions, the likelihood of being sectioned and the chance of being prescribed antipsychotics and mood stabilisers.

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Community development, networking and neighbourhood change


Jenny Fisher takes on an Australian study about community development and how umbrella bodies work for networking between organisations and neighbourhoods. She considers the implications of the findings for the UK refers to some other helpful research on the topic.

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Woodland walks and your ‘Elf

walking in woods

Kirsten Lawson dons her walking boots and reports on the national Walks for Health (WfH) programme, which has been investigated in an observational study looking at the mental, emotional and social well-being of people who participate in woodland walks.

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