New meta-analysis finds methadone better than buprenorphine for treatment retention in opioid dependence

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Ian Hamilton considers a new Lancet Psychiatry systematic review and meta-analysis that examines the effectiveness of buprenorphine versus methadone for the treatment of opioid dependence, drawing from observational and randomised controlled studies.

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Sitting in the waiting room: what happens when anxiety disorders are left untreated?

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In her debut blog, Beth Hindhaugh summarises a systematic review and meta-analysis of 173 studies examining the untreated course of anxiety disorders, which finds that for some people, anxiety disorders can improve without treatment.

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Suicide and self-harm in children: prevalence rates cause for concern

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In Mahmoud Arif’s debut blog, he and Rasanat Fatima Nawaz summarise a meta-analysis published in The Lancet Psychiatry, which estimated the prevalence rates of self-harm behaviours and suicidal ideation in children aged 12 years and under.

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Cellular immune phenotypes of depression: a gateway to precision medicine 

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In her debut blog, Fabiana Corsi-Zuelli summarises a recent systematic review and meta-analysis investigating the role of peripheral immune cells in depression, with a focus on implications for future immunotherapy trials.

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The international prevalence of suicidal ideation and behaviour in youth

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Lucy Barrass summarises a systematic review published in the Journal of the American Academy of Child & Adolescent Psychiatry that explores the international prevalence of suicidal ideation and behaviour among young people across global regions.

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Interventions to foster resilience in nursing staff may help (a little) in the short-term

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Olga Lainidi summarises a recent systematic review and meta-analysis investigating the effectiveness of resilience interventions on the mental health of nursing staff.

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Add on iCBT: weak evidence of modest benefits in depression and anxiety

iCBT can be effective in reducing symptoms of depression, anxiety, OCD and PTSD - could its accessibility help reach more people?

Liesbeth Tip and Antigone Lanitis reflect on a recent systematic review and meta-analysis that investigated internet-delivered psychological treatment as an add-on to treatment as usual in depression, anxiety, and PTSD.

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Computerised CBT for youth anxiety and depression: a growing evidence-base

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In her debut blog, Jemma Baker reports on a systematic review and meta-analysis investigating the effectiveness of computerised cognitive behavioural therapy (CBT) for depression and anxiety in adolescents.

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Is trauma a transdiagnostic risk for mental health problems? Recent umbrella meta-analysis suggests yes

Mental health services worldwide operate using discrete categories, but significant symptom overlap between different mental health disorders suggests that transdiagnostic approaches may be plausible.

In her debut blog, Megan Bailey summarises an umbrella review of systematic reviews and meta-analyses on whether psychological trauma can be considered as a transdiagnostic risk factor for mental health disorders.

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Are the kids alright? Emergency help for suicide and self-harm during the COVID-19 pandemic

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In her debut blog, Molly McCarthy appraises a recent Lancet Psychiatry systematic review and meta-analysis exploring the patterns of paediatric emergency department visits for suicide attempts, suicidal ideation, and self-harm incidents before and during the COVID-19 pandemic.

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