psychosis

Psychosis is a condition that affects a person’s mind and causes changes to the way that they think, feel and behave. A person who experiences psychosis may be unable to distinguish between reality and their imagination. People who are experiencing psychosis are sometimes referred to as psychotic. They may have hallucinations (where you see or hear things that are not there) and/or delusions (where you believe things that are untrue).

Our psychosis Blogs

Cardiovascular screening for people with severe mental illness: still missing the full picture

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Only 35% of people with severe mental illness received all six cardiovascular risk factor checks within one month in this UK primary care study. Financial incentives temporarily increased comprehensive screening but effects were uneven and short-lived. Young men of non-White ethnicity were most likely to miss screening, highlighting persistent inequalities.

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The Challenge of VR for voices in psychosis

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We’ve been talking about VR for voices for more than a decade. Are the results finally catching up with the hype? A new multi-site RCT from Denmark tests a refined, immersive version of AVATAR therapy for people with schizophrenia who continue to hear distressing voices despite medication.

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How childhood trauma affects our ability to understand minds: a systematic review of mentalisation in clinical populations

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What happens when childhood trauma disrupts our ability to understand what others think and feel? This systematic review pulls together 29 studies across psychiatric diagnoses to explore how early neglect and abuse shape mentalisation, and what that means for prevention, assessment, and care.

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Racism and psychosis: how discrimination shapes mental health risk

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People from racialised communities face higher risks of psychosis, yet racism itself is rarely studied. A new umbrella review shows why discrimination needs to be recognised as a genuine risk factor, not just a background influence.

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Targeting distressing mental imagery in psychosis: a neglected but promising area for intervention

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What if therapy focused not on thoughts or voices, but on the vivid images that often accompany them? The iMAPS-2 trial tested a novel imagery-focused therapy for psychosis, showing it’s safe, acceptable, and ready for a full-scale trial.

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Doubling of respiratory deaths in people with severe mental illness

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People with severe mental illness are more than twice as likely to die from respiratory disease than those without. This new systematic review highlights the scale of the problem and why action on public health and social inequality is just as vital as stop-smoking advice.

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Silencing the voices? Landmark German study finds rTMS modestly effective for auditory hallucinations

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A large multicentre trial from Germany found that repetitive Transcranial Magnetic Stimulation (rTMS) significantly reduced auditory hallucinations compared to sham treatment. Could this safe and well-tolerated therapy finally offer new hope for people with persistent voices?

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Treating ADHD in psychosis: What does the evidence say about safety?

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How safe is it to treat ADHD in people with schizophrenia spectrum disorders? New long-term data offers pragmatic reassurance, but also some warnings.

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Clozapine and infection risk: new evidence from Hong Kong’s 20-year cohort study

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Clozapine is described as the gold standard treatment for schizophrenia but a new cohort study suggests it is associated with an increased risk of infections, particularly in older patients, further solidifying the case for holistic care.

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Spotting the storm before it breaks: mapping the prodrome of severe mental illness

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People with severe mental illness often face years of poor health before diagnosis. A new study uses machine learning and clinical notes to map the early warning networks of symptoms that could help us intervene earlier.

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