Depression in patients with alcohol use disorders


Sally Adams summarises a recent meta-analysis of outcomes for independent and substance-induced disorders in people with depression and alcohol use disorders.

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Pharmacotherapy for anxiety and comorbid alcohol use disorders


Natasha Clarke summarises a recent Cochrane review of pharmacotherapy for anxiety and comorbid alcohol use disorders, which found only very low quality evidence about the effectiveness of medication (buspirone, paroxetine, sertraline) for treating patients with both conditions.

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Impaired inhibitory control in addiction


Maartje Luijten, Assistant Professor at the Behavioural Science Institute at Radboud University, writes her debut blog on a recent meta-analysis of deficits in behavioural inhibition in substance abuse and addiction.

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Alcohol use disorders and mortality in Nordic countries


Andrew Jones appraises a recent study of mortality and life expectancy of people with alcohol use disorders in Denmark, Finland and Sweden, which provides some useful insight into the impact of hazardous alcohol use.

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CBT for insomnia in psychiatric populations: an effective alternative to hypnotics?

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Amy Green appraises a systematic review of CBT for insomnia (CBTi) in people with comorbid mental illness, which concludes that cognitive behaviour therapy could be an effective alternative to hypnotics. However, concerns about the review methodology cast some doubt on the findings.

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Alcohol misuse and PTSD comorbidity: a significant problem lacking solutions


Current NICE guidelines state that PTSD should not be dealt with unless alcohol dependence is first treated. Paul Christiansen summarises a systematic review of the comorbidity between PTSD and alcohol misuse and wonders where the guidance leaves patients and professionals.

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Acamprosate and oral naltrexone may improve consumption related outcomes for people with alcohol use disorders


A new systematic review suggests that, when used alongside psychosocial interventions, medication can result in better alcohol consumption outcomes for people with drinking problems.

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Should we be prescribing medication to help people with alcohol use disorders?


Alcohol Use Disorders (AUDs) are common, chronic conditions which cause substantial harm to the individual and society. They are associated with substantial morbidity (Schuckit, 2009) and responsible for approximately 4% of all deaths annually. The approximate cost of AUDs to the National Health Service is upwards of £3 billion per year. Less than one-third of [read the full story…]

Targeted mindfulness-based relapse prevention may support long-term outcomes for substance use disorders


Approximately 10.6% of individuals with Substance Use Disorders (SUD) in the US seek treatment, with 40-60% relapsing within a year (Dept of Health and Human Services, 2008; McLellan et al, 2000). This highlights a real need for substance abuse treatment that focuses on relapse prevention. This blog summarises a recent RCT from JAMA Psychiatry on [read the full story…]

New evidence update from NICE on the prevention of problem drinking


The National Institute for Health and Care Excellence (NICE) has recently published an evidence update focussed on preventing harmful drinking. This update builds upon previous recommendations (NICE PH24, 2010) and is aimed at increasing awareness of the latest evidence available. Furthermore, the update indicates whether any new research may have potential impact on future NICE [read the full story…]