Alex Pike and Jonathan Roiser appraise and summarise a recently study in the Brain Stimulation journal, which looks at the long-term efficacy and quality of life of deep brain stimulation for severe depression.
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This review of the effectiveness of locally delivered adjunctive antibiotic treatment during periodontal surgery on clinical outcomes included 9 RCTs. While the findings suggested that adjunctive locally delivered antibiotics could improve some clinical sutcomes they evidence was limited and of very low certainty.
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15 systematic reviews were included in this review of teh treament and management of medication-related osteonecrosis of the jaw (MRONJ). The reviews only identified weak evidence to support treatment protocols for MRONJ so high quality well reported RCTs are needed.
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Rational commissioning This report describes a project, led by Right Care, to involve surgeons in the commissioning decision-making process, because observations made by the Department of Health and Surgical Specialty Associations showed that there were inconsistencies in the rates of elective surgical procedures between Primary Care Trusts, and that sometimes existing surgical procedures were “classified [read the full story…]
