Deep brain stimulation for severe depression: could ‘brain pacemakers’ be the answer for some?

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Alexandra Pike, Alexis An Yee Low and Jonathan Roiser critically appraise a recent n-of-1 study on ‘brain pacemakers for depression’, which received extensive press coverage earlier this month. The case study looks at deep brain stimulation (closed-loop neuromodulation) in an individual with treatment-resistant depression.

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Can we treat cognitive deficits in schizophrenia through electrical brain stimulation?

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Stefanie Sturm summarises a recent systematic review on improving cognitive deficits in schizophrenia using Transcranial Direct Current Stimulation (tDCS), a form of electrical brain stimulation.

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