Results: 371

For: cohort study

Do hobbies protect against adolescent substance misuse? Not so fast…

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A new study claims hobbies reduce substance misuse in adolescents, but are we mistaking correlation for causation? Before we start fiddling with interventions, this blog explores the risks of jumping to conclusions.

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Should you start metformin whenever you start antipsychotics?

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Guidelines say metformin can help prevent weight gain from antipsychotics like olanzapine, but this large UK study shows it’s rarely prescribed. What’s stopping us?

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Is intolerance of uncertainty in preschool children a risk factor for later anxiety?

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Do preschoolers who struggle with tolerating uncertainty get more anxious as they grow older? This longitudinal study followed preschool children across three timepoints, and found that the two are strongly related, but the rest of the picture is not as clear cut.

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Genes, brains and self-harm: New study links adolescent risk to biology and disadvantage

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Self-harm is common among adolescents and a strong predictor of suicide risk. A major new cohort study in the British Journal of Psychiatry explores how genetic risk and brain differences might explain who’s most at risk, and why.

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suPAR step forward? Teenage trauma linked to chronic inflammation in new study

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Not all childhood trauma has the same biological impact. A new study finds that adversity in late childhood is most strongly linked to immune dysregulation at age 24.

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Adolescent versus adult depression: Is risk of recurrence the same?

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Is teenage depression more likely to come back later in life? A new population study challenges assumptions and finds similar recurrence risks in both adolescents and adults.

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Clozapine and infection risk: new evidence from Hong Kong’s 20-year cohort study

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Clozapine is described as the gold standard treatment for schizophrenia but a new cohort study suggests it is associated with an increased risk of infections, particularly in older patients, further solidifying the case for holistic care.

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The genetic link behind sleep problems, cognitive dysfunction, and neuroticism in ‘treatment-resistant depression’

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A big new study suggests that certain genetic traits—like insomnia risk and neuroticism—may make depression harder to treat, while protective traits include education and cognitive ability.

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The rhythm of wellbeing: What nearly 1 million observations reveal about mood, time, and mental health

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Is there scientific truth behind the idea that things “feel better in the morning”? This new study analysed nearly 1 million responses from 49,000 people to find out how time of day, week, and year shape our mental health.

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Teen drug use today, mental health struggles tomorrow? What the evidence says

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Ian Hamilton unpacks a new study revealing how teenage substance use can pave the way to serious mental health struggles later in life. A clear warning: early use today could mean bigger problems tomorrow.

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