Targeting inflammation in depression: a proof-of-concept worth following

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A single dose of tocilizumab cleared inflammation in depressed patients, but did it ease their symptoms? A proof-of-concept RCT with cautious promise.

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suPAR step forward? Teenage trauma linked to chronic inflammation in new study

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Not all childhood trauma has the same biological impact. A new study finds that adversity in late childhood is most strongly linked to immune dysregulation at age 24.

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Patterns of inflammation in childhood and mental and cardiometabolic disorders in adulthood: mapping the trajectories

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Ruby Tsang summarises a recent longitudinal study of trajectories of inflammation in youth and risk of mental and cardiometabolic disorders in adulthood, which finds that high levels of inflammation in childhood may be linked to an increased risk of psychosis, depression and insulin resistance in early adulthood.

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