The genetic link behind sleep problems, cognitive dysfunction, and neuroticism in ‘treatment-resistant depression’

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A big new study suggests that certain genetic traits—like insomnia risk and neuroticism—may make depression harder to treat, while protective traits include education and cognitive ability.

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Targeting teenage worry: network analysis of anxiety symptoms over time

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Nervousness, irritability, excessive worry, uncontrollable worry… not all anxiety symptoms weigh the same at different ages. This new Chineses study shows how anxiety networks tighten as young people grow older, and where the best intervention targets may lie.

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“Necessary evil” or hidden harm? A scoping review of informal coercion in psychiatry

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Informal coercion – the subtle pressure patients feel in psychiatric care – is common but poorly understood. A new scoping review sheds light on how it’s defined, where it happens, and why it matters for patients and professionals alike.

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Closing the care gap: Why so few people with mental disorders receive effective treatment worldwide

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Effective treatment for mental health disorders remains the exception rather than the rule. A new 21-country study reveals where in the treatment cascade people are most likely to drop out and which factors improve the odds of getting the care they need.

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“It’s not just for attention”: New research highlights the increased risk of PMDD in women with ADHD

With better public and clinician education,  timely assessment and intervention could bypass several years of diagnostic and interventional delay, for women with ADHD and PMDD.

Women with ADHD are up to 4 times more likely to experience severe premenstrual mood symptoms than those without ADHD, especially if they also live with depression or anxiety. This new UK study shines a light on a neglected area of research, and calls for better awareness, assessment, and support.

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Under the skin: How childhood maltreatment may trigger lifelong multimorbidity

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Why do people who were maltreated as children face higher risks of both mental and physical illness? A new Mendelian randomisation study suggests that metabolic markers — like triglycerides and blood sugar — may be part of the chain connecting adversity to later multimorbidity.

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Core beliefs in psychosis: new insights from a systematic review

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Negative core beliefs like “I’m worthless” or “people can’t be trusted” are linked to hallucinations, paranoia, and suicidality. This new systematic review shows how deep-rooted schemas shape psychosis, and what this means for psychological therapies.

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Housing as care: Building recovery pathways for homeless women with severe mental illness

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Fragmented systems leave many homeless women with severe mental illness excluded from care, re-traumatised, and at risk. This study developed a gender-sensitive housing model that integrates tertiary care, transitional homes, and community reintegration; centring dignity, safety, and recovery.

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Pragmatic prescribing: why GPs offer beta-blockers for anxiety, despite guideline gaps

GPs’ perceived benefits of beta-blockers for anxiety underscore a need for further research and updated clinical guidance to align practice with evidence.

Beta-blockers like propranolol are being prescribed more often for anxiety in UK primary care, even though they don’t appear in national guidelines. This new qualitative study explores why GPs turn to them, and what that says about evidence, safety, and patient choice.

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Apples and oranges? Rethinking the evidence behind young people’s depression treatments

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What works better for young people with depression: therapy or medication? This new analysis shows why the trials may be too different to compare, and why value-based decisions matter more than ever.

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