Pharmacotherapy for PTSD: an update on the evidence finds some efficacy but small effect sizes

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Patrick Kennedy-Williams summarises a recent systematic review of pharmacotherapy for PTSD, which compares antidepressants with placebo for post-traumatic stress disorder. [Please note: this blog was amended on 7/5/15].

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Personality disorder: time for more attention and debate

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Andrew Shepherd summarises a recent series of papers in The Lancet which look at the latest research on personality disorders. This includes evidence on classification, prevalence, diagnosis, treatment and the experience of personality disorder across the life course.

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Pharmacotherapies for reducing cannabis dependence

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Kathryn Walsh reports on a recent Cochrane systematic review of pharmacotherapies for cannabis dependence, which concludes that there is a lack of evidence for all medications reviewed.

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Sustained smoking cessation intervention for hospitalised smokers

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Sally Adams summarises a new randomised controlled trial in JAMA, which tests a sustained care intervention and post-discharge smoking cessation for hospitalised smokers.

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Medication in advanced dementia: how can we judge what is appropriate?

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Caroline Struthers appraises a recent US cross-sectional study of the use of medications of “questionable benefit” in nursing home residents with advanced dementia. She concludes that all medications are of questionable value if they have side effects which might have a negative impact on quality of life or are likely to cause harm.

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Outcome and methodological comparisons in psychotherapy and pharmacotherapy meta-analyses

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Andrew Shepherd summarises a recent JAMA Psychiatry study looking at the efficacy of pharmacotherapy and psychotherapy for adult psychiatric disorders (and uses words like hubristic and existential quite a lot!)

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CAM: Many of us are using it, despite poor evidence. Whats going on?

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Complementary and alternative medicine (CAM) therapies are often perceived to be as effective as conventional treatments, more “natural”, less expensive, have fewer side-effects and are easily available without a prescription. But do these perceptions match up with the reality? Can CAM therapies be helpful additions to conventional treatments? This alludes to an interesting sociological question [read the full story…]