MDMA-assisted therapy for depression: a promising but early first step

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A small proof-of-principle trial suggests MDMA-assisted therapy may be feasible and effective for depression, but open-label design and a highly pre-treated sample urge caution.

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Circle of Security under scrutiny: NHS trial finds no added benefit for perinatal mental health

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A large NHS trial found that the Circle of Security parenting programme did not outperform treatment-as-usual for parents experiencing perinatal mental health difficulties. But does this mean we should stop offering it?

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Closing the care gap: Why so few people with mental disorders receive effective treatment worldwide

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Effective treatment for mental health disorders remains the exception rather than the rule. A new 21-country study reveals where in the treatment cascade people are most likely to drop out and which factors improve the odds of getting the care they need.

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Can we prevent major depression before it starts? A global review of psychological interventions

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Alexis An Yee Low considers a systematic review published in The Lancet Psychiatry which highlights the effectiveness of preventive psychological interventions for subthreshold depressive symptoms.

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One size fits all: could transdiagnostic therapy treat mild anxiety and depression in preadolescents?

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Charlotte Huggett and Ian McGeoghegan blog about a case study, which looks at unifying treatment for mild anxiety and depression in preadolescence.

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Therapeutic alliance and goal setting in youth mental health #ActiveIngredientsMH

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Jenna Jacob and Jermaine Dambi summarise a recent study which looks at therapeutic alliance in remote versus in-person settings.

They also present initial findings from their two active ingredients reviews which explore working alliance, collaborative goal setting and tracking for young people with depression or anxiety.

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