Shared genetic patterns found across 14 psychiatric disorders

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Psychiatric disorders share genetic variants that cluster into five main factors. Understanding shared biology could improve treatment, but more diverse genetic data urgently needed.

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Under the skin: How childhood maltreatment may trigger lifelong multimorbidity

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Why do people who were maltreated as children face higher risks of both mental and physical illness? A new Mendelian randomisation study suggests that metabolic markers — like triglycerides and blood sugar — may be part of the chain connecting adversity to later multimorbidity.

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Do psychiatric disorder genes overlap with their drug targets? And does this matter?

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Psychiatric disorders are highly heritable, but are the genes we identify in GWAS the same ones our medications target? This new study digs into the overlap and raises questions about how we develop treatments.

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Are circadian rhythms the key to understanding our physical and mental health?

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Amy Ferguson discusses the latest research exploring the role of our circadian rhythms on our health, looking at different variants in the BMAL1 gene.

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