Holly Fraser

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I am a Senior Research Associate in Immunopsychiatry researching at the University of Bristol Medical School, where I am exploring the relationship between immunological responses and psychiatric outcomes using machine learning techniques. Before this I completed my PhD in Digital Health and Care also at the University of Bristol, where I looked at using machine learning to explore predictive modelling using risk and protective factors for depression. I am passionate about many aspects of psychiatric science and mental health, particularly in psychopharmacological approaches to depression symptom management, and using novel data science methods to answer epidemiological research questions.

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Inside the diagnostic grey zone: using machine learning to separate bipolar and major depression

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High misdiagnosis rates between bipolar and major depressive disorder cause real harm to patients and services. This new neuroimaging study tested whether brain connectivity and machine learning could do a better job of telling the two apart, with interesting but limited results.

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Spotting the storm before it breaks: mapping the prodrome of severe mental illness

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People with severe mental illness often face years of poor health before diagnosis. A new study uses machine learning and clinical notes to map the early warning networks of symptoms that could help us intervene earlier.

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Predicting antidepressant response using artificial intelligence

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Holly Fraser discusses new findings on whether and how we can predict antidepressant response using artificial intelligence.

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