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Early detection of oral cancer and oral potentially malignant disorders

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This Cochrane review update of dthe iagnostic test accuracy of conventional oral examination, vital rinsing, light-based detection, mouth self-examination, remote screening, and biomarkers, used singly or in combination, for the early detection of OPMD or OSCC in apparently healthy adults included 18 studies.

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Why doesn’t parent involvement help treat children with anxiety?

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In her debut blog, Jeanne Wolstencroft summarises a systematic review finding that parental involvement in therapy doesn’t help treat children with anxiety.

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Maxillary sinus augmentation – relative performance of available biomaterials and the challenge of small studies

Sinus Lift

Mark Steven Howe takes a detailed look at this Bayesian network meta-analysis (NMA) assessing the relative performance of diffferent biomaterials used for maxillary sinus augmentation. 34 RCTs with 28 different treatment options providing a large number of potential pairwise comparisons although only a small number used direct data. The findings suggest little difference beween the various biomaterials but the available studies are small with only 5 being at low risk of bias.

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Supporting the supporters: peer support in early intervention in psychosis

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In her debut blog, Natalie Kashirsky explores a qualitative study finding valuable mechanisms of peer support in early intervention in psychosis services.

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Infrastructures fit for purpose? The complex challenges in sharing mental health data

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Louise Arsenault provides a fascinating overview on the challenges and complexities of sharing mental health data in the UK.

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The 4M model for promoting student mental health: mindfulness, movement, meaning and moderator-based interventions

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In her debut blog, Snigdha Dutta explores the 4M model for promoting university student mental health, explored by a recent systematic review which suggests that a combination of mindfulness, movement, meaning, and moderator-based interventions may help.

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Orthodontic treatment with fixed appliances – How long does it take?

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This review of the the treatment duration required to achieve whole-arch alignment of the mandibular dentition using fixed appliances included 35 RCTs. The pooled duration for whole-arch alignment in the mandible was 263.0 days/8.8 months (95%CI: 6.2 to11.3 months). Mandibular incisor alignment was achieved in 100.7 days/3.4 months (95%CI: 2.8 to 3.9 months).

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Parental loss and grief in childhood linked to an increased risk of depression in adulthood #ActiveIngredientsMH

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In her debut blog, Lauren Breen summarises a paper relevant to her Active Ingredients project, which seeks to understand the impact that grief reduction interventions can have on reducing anxiety and depression in young people aged 14-24 years.

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Tricalcium phosphates for infra-bony periodontal defects

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This review of the clinical efficacy of tricalcium phosphates (-containing) biomaterials in the treatment of periodontal infra-bony defects includes 16 RCTs. While the findings suggest improvements in pocket depth and clinical attachment level only 6 of the studies contributed to the meta-analyses and the number of events and studies are small so the findings should be viewed cautiously.

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