This blog on a review of the efficacy of platelet rich fibrin (PRF) in oral surgery procedures was prepared by MSc Students from @UClanDentistry during a workshop with the @TheDentalElf. The review includes 30 small studies of limited quality more high quality studies are needed to assess effectiveness.
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This review assessing the association between periodontitis and preterm birth included 31 studies with 20 contributing to a meta-analysis suggesting a significant positive association 2.01 (95%CI; 1.71 – 2.36).
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No new trials were available for this Cochrane review update. Only 8 RCTs were available providing inconsistent, low-quality evidence for a difference in postoperative hypersensitivity after placing a liner for posterior resin-based composite restorations in adult permanent teeth.
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Carla McEnery summarises a systematic review and meta-analysis of interventions and social functioning in youth at risk of psychosis.
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This Cochrane review of effectiveness of different fluoride concentrations of toothpaste in reducing dental caries updates the 2010 review and includes 96 RCTs. It provideds good evidence to support the benefits of using fluoride toothpaste in preventing caries and demonstrates a does response effect.
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This review of survival and technical complication rates of all-ceramic implant-supported single crowns included 41 mainly observational studies suggesting high survival rates for all-ceramic implant supported single crowns.
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Rob Poole writes his debut elf blog on a recent systematic review of trends in prescription drug misuse among women, which finds a mixed and complex picture with few conclusive findings.
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This review evaluating the evidence on the effectiveness of curcumin in the management of oral submucous fibrosis included 6 small RCTs providing inconclusive evidence of a potential benefit.
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This review of the most effective oral premedication in reducing pain in adults after nonsurgical root canal therapy including 16 studies. While a premedication of choice is suggested most outcomes are only supported by very low quality evidence.
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This review of the most effective anaesthetic solutions for inferior alveolar nerve blocks for mandibular teeth with irreversible pulpitis included 11 RCTs. The findings suggest that mepivacaine with epinephrine performed better than lidocaine with epinephrine but the number of trials is limited and the quality of evidence was very low to moderate.
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