This Cochrane review update of the effect of systemic antibiotic prophylaxis on the prevention of infectious complications following tooth extractions included 23 studies. There was very-low certainty evidence that prophylactic antibiotics may reduce the risk of infection and dry socket following third molar extraction compared to placebo.
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The Cochrane review of interdental cleaning devices, whether antibiotics are needed for dental implant placement and oral health programmes for people with intellectual difficulties were our most popular blogs of the spring.
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This review of the the effectiveness of different antibiotic protocols to prevent early dental implant failure includes 9 RCTs showing that antibiotics were protective against early implant failures.
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This review of the efficacy of antibiotic prophylaxis in dental implant placement for prevention of post-operative infection included 10 RCTs analysis indicatingthat antibiotic prophylaxis may not be necessary in health patients.
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2 reviews and 2 RCTs were discussed in this review of the effect of antibiotics on postoperative infections in orthognathic surgery. There is a lack ofclarity on the preferred antibiotic and the optimal duration of administration.
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NICE has completed a review of its 2008 guidance on antimicrobial prophylaxis against infective endocarditis following the publication of a recent study. NICE found no need to change any of its existing guidance.
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This review of antibiotic prophylaxis during dental implant placement considered both systematic reviews and RCTs. Evidence from the 10 included RCTs suggests a small reduction (2%) in the risk of implant loss. These results are similar to a recent Cochrane review.
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The latest recommendation from the ADA indicates that prophylactic antibiotics are not needed for patients with prosthetic joints undergoing dental treatments. The finding are based on 4 case-controlled trials that are considered to provide moderate evidence of no association.
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This new Cochrane review identified 11 RCTs and suggests that for those undergoing orthognathic surgery, long term antibiotic prophylaxis decreased the risk of surgical site infection compared with short-term regimens.
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This new review covers similar ground to the 2013 Cochrane review. It includes non-randomised controlled trials, but as with the Cochrane review the findings suggest that antibiotics reduce early implant failure.
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