Angharad de Cates reviews a recent Danish trial, which finds that escitalopram reduced participants’ reinforcement sensitivity compared to those on placebo. This lower reinforcement sensitivity may be similar to the emotional blunting effect often reported by patients during SSRI treatment.
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Anya Borissova reviews a French trial that claims to be evidence that “ketamine is rapid, safe in the short term, and has persistent benefits for acute care in suicidal patients”.
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In her debut blog, Jude Madani summarises the findings of the PRODIGY trial, which looked at the clinical and cost-effectiveness of social recovery therapy for the prevention and treatment of long-term social disability among young people with emerging severe mental illness.
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This well conducted randomised controlled trial assessed inferior alveolar nerve block (IANB) success of 2% mepivacaine and 4% articaine in patients with symptomatic irreversible pulpitis (SIP) in mandibular molars during access cavity preparation and instrumentation.
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Silke Vereeken summarises the INTERACT randomised controlled trial, which reports on the efficacy of Acceptance and Commitment Therapy in daily life for people with early psychosis.
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Lucy Maconick and Sonia Johnson appraise a recent trial conducted in Amsterdam, which finds that intensive home treatment substantially reduces the use of hospital beds in acute psychiatry, without compromising patient safety.
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Danielle Lamb reviews a recent large randomised controlled trial on peer support for discharge from inpatient mental health care versus care as usual in England (the ENRICH study).
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Rob Allison considers a French randomised controlled trial, which provides support for the use of peer worker–facilitated psychiatric advance directives to prevent compulsory rehospitalisation in people with severe mental illness.
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In her debut blog, Sue Brown explores an RCT from the US, which finds that computerised CBT was effective at treating depression in primary care patients, and was also beneficial to those with lower educational attainment, reading proficiency and incomes.
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Francesca Bentivegna summarises a trial which looks at how aerobic exercise can help students with major depression by examining reward and cognitive control as predictors and treatment targets.
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