Results: 675

For: randomised controlled trial

Circle of Security under scrutiny: NHS trial finds no added benefit for perinatal mental health

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A large NHS trial found that the Circle of Security parenting programme did not outperform treatment-as-usual for parents experiencing perinatal mental health difficulties. But does this mean we should stop offering it?

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Peer support has UPSIDES for global mental health

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The UPSIDES trial demonstrates that peer support is effective across diverse global contexts, from high-income to low-income countries. While overall social inclusion scores didn’t reach significance, participants showed reduced isolation and increased empowerment and hope. This landmark study proves peer support can be successfully adapted to different cultural settings while maintaining core recovery-oriented principles.

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Talking about suicide in psychosis: does a targeted therapy make a difference?

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People with psychosis face unique risks around suicide, but most treatments aren’t designed with them in mind. This new RCT tested a targeted therapy that tackles those specific challenges. So what did it find?

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GenAI chatbots can treat clinical level mental health symptoms

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With NHS services under strain, digital therapies are attracting more attention. This new study tested a generative AI chatbot in a national RCT and found significant clinical improvements. But are we ready for AI to join the therapy team?

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Will standardised questionnaires improve CAMHS care? New trial says: not necessarily

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Referrals to CAMHS have skyrocketed, but are we getting any better at diagnosing youth mental health problems? Could standardised diagnostic tools like the DAWBA help? A new RCT suggests the answer is more complicated than expected.

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AWARE and INSPIRE: school mental health trials show mixed results and unexpected harms

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The Education for Wellbeing programme, funded by the Department for Education, was one of England’s largest school-based mental health research initiatives. It included two major trials (AWARE and INSPIRE) testing universal mental health approaches in schools between 2018 and 2024. What did these big studies really find?

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Preventing the intergenerational transmission of anxiety: encouraging insights from new online RCT

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Francesca Zecchinato summarises a recent trial investigating the effectiveness of an unguided modular online intervention for anxious parents in preventing anxiety in their offspring.

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Mentalisation-based therapy for anti-social personality disorder shows promise in rare prison-based trial

The study included men aged 21 or older who were convicted of an offence and under probation at one of the 13 study sites.

RCTs are rare in prison settings, but today, Tom Stephenson and Danny Whiting blog about a new rigorous trial that provides grounds for therapeutic optimism.

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The other side of postnatal depression: what about Dads?

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Demetra Christodoulou reviews a new randomised controlled trial from Pakistan testing “Learning Through Play Plus Dads”: a group parenting programme designed to support fathers with postnatal depression.

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Culturally adapted CBT may lead to recovery from postnatal depression in British South Asian women

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Angelica Tong explores the ROSHNI-2 trial of a culturally adapted CBT programme for postnatal depression in British South Asian women.

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