Nonsurgical periodontal treatment: adjunctive antibiotic use in diabetics

Participants ranked the clinical instruments most highly

This review of adjunctive use of systemic antibiotics in nonsurgical periodontal treatment of diabetics identified 12 small RCTs. No additional benefit was seen with antibiotic use

[read the full story...]

Antibiotics as an adjunct to the non-surgical periodontal treatment of smokers

Smoking man

Mark-Steven Howe looks at a systematic review of the effectiveness of adjunctive antibiotics in smokers undergoing non-surgical periodontal treatment. While a statistical benefit was noted it was not considered to be clinically relevant.

[read the full story...]

Third molar removal: antibiotics reduced risk of dry socket

shutterstock_133048361

This review of antibiotic prophylaxis for the removal of third molars included 22 RCTs and suggest that antibiotic use lowered the infection risk by 60%. The number pf patients needed to treat to prevent one infection was 14 (95%CI;11-19).

[read the full story...]

Periodontal treatment- adjuvant antibiotics for diabetic patients?

shutterstock_2584741

This review of adjuvant antibiotics for diabetics undergoing periodontal treatment included 13 small RCTs. While a statistically significant improvement in probing depth was seen the magnitude of this improvement is unlikely to be clinically significant.

[read the full story...]

Bisphosphonate-related osteonecrosis of the jaw treatments– little evidence available

bisphosphonate

This Cochrane review of bisphosphonate related osteonecrosis of the jaw only identified one small RCT. The trial compared the use of hyperbaric oxygen (HBO) as an adjunct to standard care. While it suggested a benefit for HBO it was under powered and at high riisk of bias

[read the full story...]

Third molars: single dose of preoperative antibiotic reduced infection

shutterstock_31846396

10 RCTs were included in this review of preoperative antibiotics for removal of third molars. The use of antibiotics significantly reduced the odds of surgical site infection or alveolar osteitis (OR = 0.30; 95% CI, 0.19 to 0.47; P≤.00001)

[read the full story...]

Little evidence for antibiotic use in irreversible pulpitis

shutterstock_64158991 question mark pills tablets

This is the latest update of this Cochrane review of the effectiveness of antibiotics for irreversible pulpitis. Only 1 small RCTs is available which provides insufficient evidence to determine whether antibiotics reduce pain or not compared to not having antibiotics

[read the full story...]

Systemic antibiotics for aggressive periodontitis?

shutterstock_113989924  - periodontitis

This review of systemic antibiotics and non-surgical periodontal therapy for aggressive periodontitis included 13 RCTs and suggests a statistically significant benefit compared to non-surgical therapy alone.

[read the full story...]

Azithromycin as an adjunctive antibiotic in non-surgical periodontal therapy

shutterstock_129331361

Another new review of local or systemic azithromycin as an adjunct in non-surgical periodontal therapy includes 14 RCTs and demonstrates small benefits in periodontal parameters. However, the included studies are small and it is unclear if the benefits are clinically important.

[read the full story...]

Aggressive periodontitis: systemic antibiotics may improve outcome

shutterstock_70250746

This review and network meta-analysis included 11 small RCTs of limited quality, suggesting a statistically significant benefit for the use of adjunctive systemic antibiotics for the treatment of aggressive periodontitis.

[read the full story...]