Antibiotics to prevent bacterial endocarditis following dental procedures

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This Cochrane review update of antibiotic prophylaxis before invasive dental procedures in people at risk or at high risk of bacterial endocarditis included one case-controlled study. Consequently, there is no clear evidence about whether antibiotic prophylaxis is effective or ineffective against bacterial endocarditis in at-risk people who are about to undergo an invasive dental procedure.

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Hypomineralised second primary molars and prenatal, perinatal and postnatal exposures

HSPM  Molar-Incisor hypomineralisation

This review of adverse health conditions in the prenatal, perinatal and postnatal periods and associations with hypomineralised second primary molars(HSPM) included 14 studies. The findings suggest associations between HSPM and a number of condition but findings should be interpreted cautiously.

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Periodontitis: Locally delivered anti-microbials as an adjunct to surgical periodontal treatment

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This review of the effectiveness of locally delivered adjunctive antibiotic treatment during periodontal surgery on clinical outcomes included 9 RCTs. While the findings suggested that adjunctive locally delivered antibiotics could improve some clinical sutcomes they evidence was limited and of very low certainty.

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Periodontitis: Locally delivered antimicrobials as an adjunct to non-surgical treatment

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This review of of locally delivered antimicrobials as an adjunct to scaling and root planing (SRP) for the non-surgical treatment of patients with periodontitis included 50 RCTs. While the findings indicate statistically significant benefits for probing pocket depth and clinical attachment level (CAL) at 6-9 months and for CAL at 12-60 months their clinical importance can be questioned. In addition most of the studies(47) were considered to be at high risk of bias.

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Periodontitis: Systemic antimicrobials as an adjunct to non-surgical treatment

Periodontal disease
Periodontitis

This Cochrane review of the effects of systemic antimicrobials as an adjunct to scaling and root planing (SRP) for the non-surgical treatment of patients with periodontitis identified 45 RCTs. However the evidence is of very low certainty to inform tclinicians and patients if adjunctive antibiotics are beneficial.

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Hypomineralisation and drugs used during pregnancy and infancy

HSPM  Molar-Incisor hypomineralisation

Manas Dave looks at this systematic review of the association between hypomineralised second primary molars (HSPM) and drug use during pregnancy and the first year of life

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Top Dental Elf Blogs Apr– Jun 2019

The Dental Elf brings you daily updates of evidence-based dentistry research

The Cochrane review of interdental cleaning devices, whether antibiotics are needed for dental implant placement and oral health programmes for people with intellectual difficulties were our most popular blogs of the spring.

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Guideline: Antibiotics for Dental Pain and Swelling

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This new guideline from the American Dental Association is about the the appropriate use of systemic antibiotics for the urgent management of symptomatic irreversible pulpitis with or without symptomatic apical pulpitis, pulp necrosis and symptomatic apical periodontitis and pulp necrosis and localized acute apical abscess.

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Antibiotics and toothache

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Only 2 RCTs are included in this Cochrane review update of the effects of systemic antibiotics on adults with symptomatic apical periodontitis or acute apical abscess providing insufficient evidence of effectiveness.

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Orthognathic surgery: limited evidence on antibiotic prophylaxis?

The authors sought to review available literature relating to SSRI withdrawal syndromes

2 reviews and 2 RCTs were discussed in this review of the effect of antibiotics on postoperative infections in orthognathic surgery. There is a lack ofclarity on the preferred antibiotic and the optimal duration of administration.

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