Platelet-rich fibrin and third molar surgery outcomes

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This review of the effectiveness of platelet-rich fibrin (PRF) in reducing postoperative complications of third molar surgery included 10 small RCTs suggesting that PRF may reduce but not prevent some complications.

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Tooth socket preservation using autologous platelet concentrates

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33 studies were included in this review of the effectiveness of autologous platelet concentrates (APCs) in the preservation of fresh extraction sockets. The studies were mainly small and of less than 6 months duration suggesting a positive effect.

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Chlorhexidine gel and alveolar osteitis

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This review of the effectiveness of chlorhexidine gel for the prevention of alveolar osteitis (AO) included 10 trials published since 2010. The findings suggest a 57% reduction in incidence of AO similar to other reviews of this topic.

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Chlorhexidine gels and rinses reduce dry socket after third molar extraction

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This review of the effectiveness of chlorhexidine for prevention of dry socket after third molar removal includes 18 RCTs. The finding suggest a 47% (95%CI,38-55) reduction in cases following its use.

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Third molars: insufficient evidence for removal of impacted asymptomatic disease-free teeth

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This update of an earlier Cochrane review comparing retention or extraction of of asymptomatic disease-free impacted third molars only identified 2 studies of low to very low quality evidence providing insufficient evidence to inform practice.

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Third molar removal: antibiotics reduced risk of dry socket

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This review of antibiotic prophylaxis for the removal of third molars included 22 RCTs and suggest that antibiotic use lowered the infection risk by 60%. The number pf patients needed to treat to prevent one infection was 14 (95%CI;11-19).

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Third molars: single dose of preoperative antibiotic reduced infection

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10 RCTs were included in this review of preoperative antibiotics for removal of third molars. The use of antibiotics significantly reduced the odds of surgical site infection or alveolar osteitis (OR = 0.30; 95% CI, 0.19 to 0.47; P≤.00001)

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Dry socket prevention: eugenol dressing or chlorhexidine gel?

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This trial compared eugenol dressing or chlorhexidine gel for dry socket prevention against no intervention. Both agents reduced the incidence of dry socket but the reduction was greater with eugenol.

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Dry socket – oral contraceptives may increase incidence

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This review included 16 low-moderate quality studies, which overall suggest that the use of oral contraceptives leads to a higher incidence of dry socket. Risk ratio = 1.80 (95% CI; 1.33–2.43).

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Trial suggests that post extraction use of warm saline mouth rinse reduces complications

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The use of warm salt water mouthrinses as part of a post extraction regimen is a commonly taught, yet as the authors of this trial found there seems to be little objective evidence for its effectiveness.  The aim of this study was to determine the beneficial effect of different warm saline rinse regimens on the [read the full story…]