Enamel white spot lesions: self-application of topical fluorides for prevention and reversal

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This review of self-applied topical fluorides for the prevention reversal of enamel white spot lesions during fixed orthodontic treatment included 3 RCTs two of which were at high risk of bias.

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Chlorhexidine mouthwash: Do anti-discolouration systems reduce effectiveness?

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This review of the effectiveness of chlorhexidine mouthwash with an anti-discoloration system (ADS) is effective in preventing extrinsic tooth surface discoloration included 13 RCTs with the findings suggesting that ADS reduces staining but did not affect its properties with respect to gingival inflammation and plaque scores.

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Anti-plaque agents in toothpaste: Are they helpful in managing gingivitis?

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This review of the efficacy of different anti-plaque chemical agents in managing gingivitis included 32 RCTS of toothpastes and 19 of mouthrinses suggested greater benefits with some agents.

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Salvadora persica (Miswak) mouthrinse is it as effective as chlorhexidine mouthwash?

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This review comparing the effectiveness of Salvadora persica-containing mouthrinses against chlorhexidine or placebo included 19 studies providing low to very low quality evidence of its effectiveness.

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Aloe vera mouthwash: how does it compare with chlorhexidine?

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This review of the efficacy of aloe vera mouthrinse on plaque and gingival inflammation includes 6 RCTS providing very low quality evidence that aloe vera mouthwash is comparable to chlorhexidine in reducing gingival inflammation.

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Chlorhexidine-fluoride mouthwash efficacy

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This review of the efficacy of a chlorhexidine mouthwash containing sodium fluoride compared to a chlorhexidine mouthwash alone includes 10 small short term studies that suggests the findings are similar for both preparations.

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Chlorhexidine mouthrinse: Reduced plaque and gingivitis when used as adjunct to mechanical oral hygiene procedures

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51 studies were included in this Cochrane review of chlorhexidine mouthwash as an adjunct to mechanical oral hygiene measures. The review provides high quality evidence for a large reduction in the build-up of plaque at 4 to 6 weeks or 6 months. There is also high quality evidence of a moderate reduction in gingivitis in patients with mild gingivitis which may not be clinically important.

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Oral mucositis in cancer patients: no benefit from chlorhexidine mouthwash

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This review of chlorhexidine (CHX) for prevention & treatment of oral mucositis included 12 RCTs with 9 contribution to the meta-analysis. CHX was not significantly effective in preventing mucositis or reducing its severity.

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Tranexamic acid for minor oral surgery in anticoagulated patients

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5 good but small RCTs were identified for this review of topical tranexamic acid (TXA) for minor oral surgery in patients on anticoagulants. The findings suggest that TXA irrigation and mouthwash may reduce the risk of bleeding.

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Dentine hypersensitivity: do mouthwashes help?

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This review of mouthwashes for the management of dentine hypersensitivity included 7 small studies all at high risk of bias. While minor benefits in patients’ subjective perception were seen the limited quality of the study means these findings should be interpreted with caution.

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