Antiseptics as adjuncts to nonsurgical periodontal treatment

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This review of the effectiveness of adjunctive local antiseptics to conventional scaling and root planning (SRP) included 12 RCTs only 3 of whihc were considered to be at low risk of bias. While the findings suggest some benefit from the use of antiseptics with a sustained-release delivery the limited quality of the included studies means that the findings should be interpreted cautiously.

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Probiotics for the treatment of gingivitis

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This review of the the efficacy of probiotics in the treatment of gingivitis included 10 small short term studies providing limited weak evidence for any effect on gingivitis.

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Hyaluronic acid as an adjunct to periodontal treatment

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This review looked at the adjunctive effects of hyaluronic acid (HA) on surgical or non-surgical periodontal treatment. Thirteen RCTs the majority at high risk of bias suggested that the topical application of HA may lead to additional clinical benefits.

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Dual antiplatelet therapy and post-operative bleeding following minor oral surgery

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This review of bleeding complications in patients on dual antiplatelet therapy compared to patients on single antiplatelet or no antiplatelet therapy for patients undergoing oral surgery included 16 studies but no randomised trials. Findings suggest that dual antiplatelet therapy should not be discontinued but the evidence is of low quality.

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Doxycycline as an adjunct to scaling and root planning in diabetics

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This review of the effectiveness of systemic doxycycline as an adjunct to scaling and root planning (SRP) with SRP alone in diabetic patients with periodontitis included 6 small RCTs suggesting no additional benefit from systemic docycycline.

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Periodontal disease: Influence of influence family/parent characteristics

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This review of the influence family/parent characteristics on periodontal disease in children and adolescents included 32 onsevations studies suggesting that parental income, education and occupation are assocated with periodontal disease.

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Interdental cleaning devices for prevention and control of caries and periodontal disease

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Thi Cochrane review evaluateingthe effectiveness of interdental cleaning devices used at home, in addition to toothbrushing, compared with toothbrushing alone, for preventing and controlling periodontal diseases, caries, and plaque includes 35 RCTs providing low to very low certainty evidence that floss or interdental brushes in addition to toothbrushing may reduce gingivitis or plaque, or both.

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Chlorhexidine mouthwash after periodontal or implant surgery

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This review of the benefits of chlorhexidine rinsing after periodontal or implant surgery included 11 small RCTs which provide very low quality evidence of a benefit.

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Anticoagulants and post-operative bleeding following oral surgery

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This review of the post oral surgery bleeding risk for patients on direct oral anticoagulants (DOACs) included 13 observational studies. The findings suggest a three-fold increase in bleeding for those patients on DOACs although the quality of the available evidence is limited.

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Bleeding after dental extraction: no evidence from randomised trials

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This update of a 2016 Cochrane Oral Health Group review of interventions for post extraction bleeding was unable to identify any published or ongoing trials assessing interventions. Well conducted and reported randomised controlled trials are needed on this question.

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