Curcumin as an adjunct to scaling and root planing for chronic periodontitis

Tumeric, curcumin

This review of the effectiveness of oral curcumin products in reducing gingival inflammation and probing pocket depth in adults included 27 RCTs.The findings suggest that curcumin products were as effective as other products. However, a majority of the studies are small and none are at low risk of bias.

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Periodontitis: Adjunctive amoxicillin and metronidazole with full-mouth scaling and root planing

This review of whether amoxicillin and metronidazole used as an adjunct to full-mouth scaling and root planing improved clinical outcomes included 11 RCTs. While the findings indicate significant improvements in clinical attachment level and pocket probing depth they may not be clinically important.

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Periodontitis: Locally delivered anti-microbials as an adjunct to surgical periodontal treatment

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This review of the effectiveness of locally delivered adjunctive antibiotic treatment during periodontal surgery on clinical outcomes included 9 RCTs. While the findings suggested that adjunctive locally delivered antibiotics could improve some clinical sutcomes they evidence was limited and of very low certainty.

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Peri-implantitis: Are locally administered antibiotics effective?

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This review of the effectiveness of locally administered antibiotics in the treatment of peri-implantitis included 12 small studies 7 of which were RCTs. While the findings suggest a small additional benefit with antibiotic use however the clinical importance of this is debatable.

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Diabetes and periodontal status in children and adolescents

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This review comparing the periodontal status of normal children with those living with diabetes regardless of type included 11 studies. While the findings suggest that children and adolescents with diabetes have poorer periodontal status the quality of the evidence is low.

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Orthodontic ligation methods and biofilm formation

iStock_000002551343XSmall colourful braces on teeth

This review comparing elastomeric ligation with self-ligation and steel wire ligation for orthodontic appliances and their effect on clinical outcomes included 11 RCTs. The findings suggest no significant differences although the trials were small with a majority at high risk of bias.

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Clarithromycin as an adjunct to non-surgical periodontal treatment

plaque,calculus,periodontal disease

This review of systemic or locally delivered clarithromycin as an adjunct to non-surgical periodontal therapy included 7 small RCTs, 4 RCTS related to systemic use and 3RCTS for local application. The findings provide moderate certainty evidence suggesting locally delivered clarithromycin significantly improves treatment outcome

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Chronic periodontitis: Efficacy of adjunctive antimicrobials

Many drugs are licensed for use in Generalised Anxiety Disorder (GAD), but it is unclear what works best.

This review of the efficacy of antimicrobials adjunctive to scaling and root planing (SRP) in the treatment of chronic periodontitis. 21 RCTs were included with the findings showing that amoxicillin and metronidazole had the largest statistical benefit. Whether this benefit is a clinically important benefit is a wider question.

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Boric acid as an adjunct to non-surgical periodontal therapy?

gum disease, scale and polish

Non-surgical periodontal treatment is the mainstay of treatment for the management of periodontitis. A number of adjunctive treatments have been used to improve outcomes including, local and systematic antibiotics and photodynamic therapy.  It has been suggested that boric acid may be beneficial as boron compounds have antimicrobial, anti-inflammatory and immune regulatory effects and beneficial effects [read the full story…]

Smoking and its impact on non-surgical periodontal therapy

gum disease, scale and polish

This review of the impact of smoking on clinical outcomes of non-surgical periodontal treatment included 17 cohort studies of whihc 11 were prospective. The findings suggest statistically significant smaller improvements in the smoking that non-smoking group. However, any differences are modest and my not be clinically important.

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