This review evaluating the efficacy of subgingival instruments for the treatment of periodontitis included 19 RCTs. The findings show that mechanical subgingival instrumentation is efficacious in the nonsurgical treatment of periodontitis, irrespective of type of instrument or mode of delivery.[read the full story...]
4 RCTs involving 96 patients were included in this review of osseous resective surgery (ORS) in the treatment of residual periodontal defects.
The findings suggest some benefit from ORS but they should be interpreted cautiously because of the limited number of small studies.
This review of the effectiveness of adjunctive local antiseptics to conventional scaling and root planning (SRP) included 12 RCTs only 3 of whihc were considered to be at low risk of bias. While the findings suggest some benefit from the use of antiseptics with a sustained-release delivery the limited quality of the included studies means that the findings should be interpreted cautiously.[read the full story...]
This review of minimally invasive periodontal surgery for the treatment of intra‐bony defects included 25 studies of which 10 were randomised controlled trials. There is limitied evidence comparing minimal and traditional approach but minimal invasive surgery may produce similar outcomes.[read the full story...]
This review evaluating the potential efficacy of mesenchymal stem cells in periodontal regeneration included 15 small studies of very low quality. Additional high quality RCTs are neeeded to assess effectiveness before clinicial use.[read the full story...]
This review looked at the adjunctive effects of hyaluronic acid (HA) on surgical or non-surgical periodontal treatment. Thirteen RCTs the majority at high risk of bias suggested that the topical application of HA may lead to additional clinical benefits.[read the full story...]
This review of the effectiveness of systemic doxycycline as an adjunct to scaling and root planning (SRP) with SRP alone in diabetic patients with periodontitis included 6 small RCTs suggesting no additional benefit from systemic docycycline.[read the full story...]
38 RCTs were included in this Cochrane review of the effects of autologous platelet concentrates (APC) used as an adjunct to periodontal surgery. Very low quality evidence was found for two approaches involving open flap debridement.[read the full story...]
This Cochrane review of the efficacy of different root coverage procedures for gingival recession included 48 RCTs describing a range of procedures. Most procedures led to a reduction in gingival recession.[read the full story...]
This review of the effectiveness of regenerative periodontal treatment for preventing periodontal defects following third molar surgery included 21 RCTs and suggested that these approaches were effective. However a majority of the included studies were at high risk of bias so the findings should be interpreted cautiously.[read the full story...]