Antiseptics as adjuncts to nonsurgical periodontal treatment

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This review of the effectiveness of adjunctive local antiseptics to conventional scaling and root planning (SRP) included 12 RCTs only 3 of whihc were considered to be at low risk of bias. While the findings suggest some benefit from the use of antiseptics with a sustained-release delivery the limited quality of the included studies means that the findings should be interpreted cautiously.

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Chlorhexidine gel as an adjunct to non-surgical periodontal treatment

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This review of the efficacy of adjunctive subgingival administration of chlorhexidine gel in nonsurgical periodontal treatment for chronic periodontitis included 17 RCTs only one of which was at low risk of bias for all domains. Findings suggest an improvement in pocket probing depth but not for clinical attachment.

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Halitosis: What are the best methods of prevention and control?

According to this review, Venlafaxine, Pregabalin, Escitalopram, and Duloxetine are viable alternatives to traditional drug treatment for generalised anxiety disorder.

44 RCTs were included in this Cochrane review assessing interventions for the prevention and control of halitosis. Only low to very-low cetrainty evidence was identified so conclusions regarding the superiority of any intervention could not be drawn.

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Periodontal treatment to prevent or manage cardiovascular disease

gum disease, scale and polish

Two small RCTs at high risk of bias were included in this Cochrane systematic review looking at the effects of periodontal therapy for primary or secondary prevention of CVD in people with chronic periodontitis.

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Doxycycline as an adjunct to scaling and root planning in diabetics

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This review of the effectiveness of systemic doxycycline as an adjunct to scaling and root planning (SRP) with SRP alone in diabetic patients with periodontitis included 6 small RCTs suggesting no additional benefit from systemic docycycline.

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Diabetic patients: does periodontal treatment improve glycaemic control?

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91 diabetic patients were randomised to non-surgical scaling and root planing and amoxicillin or control. While periodontal status significantly improved at 3 months there was no no significant effects on
glycaemic control.

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Metformin as an adjunct to periodontal treatment

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This review of metformin as an adjunct to scaling and root planing for chronic periodontitis included 5 RCTs that were of limited quality and mainly from one research group. The findings suggest benefit.

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Phytotherapy as an adjunct to nonsurgical periodontal treatment?

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7 small RCTs that majority of cross-over design were included in this review of phytotherapy as an adjunct to scaling and root planing for chronic periodontitis. While the findings suggest a benefit these should be viewed with caution until results from larger high quality studies are available.

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Statins as an adjunct to scaling and root planing

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11 RCTs were included in this review of statins as an adjunct to scaling and root planing. The findings suggest improvements in pocket depth and clinical attachment levels with statin use.

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