Cognitive functioning in psychosis: is neuropsychological decline continuous, generalised, and specific to schizophrenia?

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Emmeline Lagunes Cordoba and Derek Tracy explore a case control study that looks at cognitive change in people with schizophrenia and other psychoses in the decade following the first episode.

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Low dose Amisulpride for very late onset schizophrenia-like psychosis: the ATLAS study

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Elwira Lubos summarises the recent ATLAS RCT of antipsychotic treatment for very late-onset schizophrenia-like psychosis, which provides evidence for the effectiveness of a very low dose of Amisulpride (100 mg).

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How does age at onset affect outcomes in schizophrenia?

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Geoff Davies publishes his debut elf blog about a recent systematic review and meta-analysis looking at age at onset and the outcomes of schizophrenia.

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No good quality research to guide the treatment of late-onset schizophrenia

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Late-onset schizophrenia is relatively common. Onset after the age of 40 years is reported in 23% of patients hospitalised with schizophrenia. The condition is different from early-onset schizophrenia on a number of counts, including the response to antipsychotic drugs. This Cochrane review set out to assess the effects of antipsychotic drugs for elderly people with [read the full story…]