Manas Dave is an NIHR Academic Clinical Fellow in Oral and Maxillofacial Pathology and Honorary Lecturer in Dentistry at The University of Manchester. Manas graduated from the University of Manchester with degrees in Pathology and Dentistry before undertaking General Professional Training in the North East. During this time, he achieved qualifications in Pathology Informatics and Medical Education. He is currently studying a Masters degree in Dental Public Health.
In this blog Manas Dave looks at a systematic review examining plagiarism in dentistry. Twenty nine studies produced 23 datasets for assessment with the authors concluding that some level of plagiarism was unavoidable but needs to be managed by open discussion.
Manas Dave takes a look at this review aiming to identify the potential risk factors associated with the development of oral mucositis in paediatric patients. While a range of risk factos are higlighted it is worth noting that 80-100% of all children having chemotherapy experience some degree of mucositis.
This review of the distribution of histological subtypes, treatment and overall survival (OS) rates of head and neck sacomas included 8 studies from 6 countries. Meta-analysis (5 studies) found the 5-year OS = 74%(95%CI; 63 to 84%)
This review of the use and diagnostic accuracy of saliva tests for the detection of SARS-CoV-2 included 16 studies. THe findings suggests good diagnostic accuracy but furteher research is needed to determine confounding factors such as method and time of sample collection, transport medium, storage etc. prior to population testing.
This systematic review and network meta-analysis comparing interventions for the management of oral lichen planus included 55 RCTs. While the findings suggested that topical corticosteroids may be most effective the evidence is of low to very low certainty.
Manas Dave looks at a review of the diagnostic accuracy of blood and salivary microRNAs (miRNAs) in discriminating oral squamous cell carcinoma. The review included 20 cross-sectional studies and suggested moderate diagnostic accuracy and higlights a potential are for larger scale studies.
This review of the possible association between diabetes mellitus and dental implant complications included 10 cohort studies (8 prospective 2 retrospective). The findings suggest that patients with diabetes are more likely to have clinical complications with dental implants.
This review of the use of as a sample for the detection of SARS-COV-2 included 22 studies ( 2 case reports, 17 case series and 3 mass screenings) while SARS-CoV-2 is detected in saliva additional high quality studies are needed to determine efficacy.
This review of the potential association between zinc levels and occurrence of Recurrent aphthous stomatitis (RAS) included 19 case-controlled studies. The findings show a sigificant association between low zinc levels and RAS.