Osteoradionecrosis and tooth extraction before radiotherapy

radiotherapy

This review of the osteoradionecrosis rate in patients with head and neck cancer having toothth extraction performed before radiotherapy included 8 mainly retrospective studies. The pooled incidence rate was estimated at 2.2% (95% CI: 0.6% to 3.9%) although none of the studies controlled for other risk factors.

[read the full story...]

Intraoral stents to reduce oral toxicity of radiotherapy

Varian TruBeam Linear Accelerator, Rathiotherapy

This review assessing the effectiveness of intraoral stents in reducing toxicities in oral cavity induced by radiotherapy in head and neck region included 7 small studies. While the analysis suggests a beneficial effect from the use of intraoral stents the included studies only provide verylow certainty evidence so further high-quality RCTs are needed.

[read the full story...]

Osteoradionecrosis incidence and the timing of dental extractions

radiotherapy

This review of whether the incidence of osteoradionecrosis differed between patients who have dental extractions before or after radiotherapy (RT) included 24 studies (19 retrospective 5 prospective). While the findings suggest that the incidence is similar if extractions are undertaken before or after RT the quality of the evidence is limited.

[read the full story...]

Low-level laser therapy in the prevention and treatment of oral mucositis

iStock_000001604217XSmall dental laser

Manas Dave takes a look at this review evaluating the prophylactic and therapeutic effects of low-level laser therapy (LLLT) in patients who might or have developed oral mucositis during chemotherapy or radiotherapy.

[read the full story...]

Osteoradionecrosis and denture use in head and neck cancer patients

craig-cameron-cWRVSX6lfBg-unsplash-amd

This review assessing the evidence of the impact of replacing missing teeth with dentures on the development of osteoradionecrosis in patients who have radiotherapy for head and neck cancer only identified 3 case-controlled studies of very low quality.

[read the full story...]

Osteoradionecrosis of the jaws: Prevention in adult patients with head and neck cancer

radiotherapy

This Cochrane review of interventions for preventing osteoradionecrosis of the jaws in adults with head and neck cancer undergoing curative or adjuvant (i.e. non-palliative) radiotherapy included 4 RCTs. The limited quality of the available studies means evidence regarding the interventions evaluated in this review is uncertain.

[read the full story...]

Oral mucositis in cancer patients: the effect of oral supplementation

shutterstock_74662099 zinc

This review of of the effects of oral supplementation on the prevention and/or treatment of oral mucositis in patients with cancer undergoing chemotherapy and/or radiotherapy included 12 RCTs and suggest that Zinc supplements may be beneficial.

[read the full story...]

Drugs to prevent salivary gland damage following radiotherapy to the head and neck

This Cochrane review of drugs for the prevention of radiation-induced salivary gland dysfunction included 39 studies, while a range of agents was tested the evidence found is not sufficient to highlight much promise in terms of effective preventative treatments.

[read the full story...]

Oral Mucositis: can honey reduce its severity?

honey-1089508_1920

This review of the use of honey to educe the severity of radio/chemotherapy-induced oral mucositis identified 7 low quality RCTs that suggest that use of honey may reduce the severity of oral mucositis.

[read the full story...]

Dental Implants: survival rate in irradiated patients

shutterstock_34428667

40 studies were identified for this review of dental implants in irradiated patients. While survival rates were good, they were lower than in non-irradiated areas. As the majority of the included studies were retrospective the findings should be viewed cautiously.

[read the full story...]