Gut microbiome disruptions in depression: shifting the focus to metabolic signatures in blood

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Gerard Clarke explores a recent study which looks into the interplay of metabolome and gut microbiome in individuals with major depressive disorder.

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Does what you eat affect how you feel?

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Daisy Crick summarises a recent paper on the casual relationship between polyunsaturated fatty acids and depression.

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New genes implicated in Alzheimer’s disease #LetsTalkMentalHealthII

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Byron Creese writes a #LetsTalkMentalHealthII blog about a recent genome-wide meta-analysis which identifies new loci and functional pathways influencing Alzheimer’s disease risk.

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Higher body mass index is associated with a lower subjective wellbeing

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Benjamin Janaway explores a recent mendelian randomisation study that looks at the causal effects between subjective wellbeing and cardiometabolic health.

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Risk factors and peripheral biomarkers for schizophrenia spectrum disorders

This 'umbrella review' aimed to systematically appraise the meta-analyses of observational studies on risk factors and peripheral biomarkers for schizophrenia spectrum disorders.

Marcus Munafo considers the findings of a systematic review of meta-analyses of observational studies, which looks at risk factors and peripheral biomarkers for psychotic disorders on the schizophrenia spectrum.

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Psychiatric genomics: an update and an agenda

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Marcus Munafo comments on a review of the work of the Psychiatric Genomics Consortium, which in recent years has delivered an increasing flow of new knowledge about the fundamental basis of common psychiatric disorders.

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Early menarche associated with depressive symptoms in early adolescence

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Emily Stapley summarises a Mendelian randomisation study that investigates associations between the timing of menarche with depressive symptoms and depression in adolescence.

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