From weight gain to heart rhythm changes, sexual dysfunction to sleep problems — the physical side effects of psychiatric drugs are vast, complex, and often overlooked. This blog distils key insights from a new Lancet Commission published today; to help clinicians and patients make safer, more informed prescribing decisions.
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People with psychosis face unique risks around suicide, but most treatments aren’t designed with them in mind. This new RCT tested a targeted therapy that tackles those specific challenges. So what did it find?
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RCTs are rare in prison settings, but today, Tom Stephenson and Danny Whiting blog about a new rigorous trial that provides grounds for therapeutic optimism.
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Fionnuala Rogers discusses a study on the role of white matter microstructure in depression-related cognitive dysfunction, which highlights the importance of viewing major depressive disorder not only as a mood disorder, but as a condition with significant neurocognitive implications.
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Alexis An Yee Low considers a systematic review published in The Lancet Psychiatry which highlights the effectiveness of preventive psychological interventions for subthreshold depressive symptoms.
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Lorna Staines considers recent studies in psychological interventions, to support affordable healthcare for South Asian women with postnatal depression.
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This Swedish cohort study, blogged by Duncan Swiffen, is yet more evidence for lithium as an excellent treatment for people with bipolar disorder. This time it comes out on top in terms of preventing depression-related hospitalisation.
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Kirsten Lawson and Douglas Badenoch review the new randomised controlled trial by Cleare et al, published today in The Lancet Psychiatry, directly comparing the clinical and cost effectiveness of lithium and quetiapine as augmentation treatments for patients with ‘treatment resistant depression’.
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Laura Hemming explores a new systematic review out today in The Lancet Psychiatry, which stresses the importance of involving of people with lived experience of mental health disorders in co-developing research outcome measures.
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Kalya Win Aung, Angela Kibia and Dorothy Williams consider a systematic review and network meta-analysis published by the Lancet Psychiatry on psychological and psychosocial interventions for treatment-resistant schizophrenia.
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