Inflammation and depression: new insights into sex differences in adolescents

Illustration set of 9 different faces of all sexes and races . Also available in other sets.

Sophie Fairweather explores a recent paper which suggests that the inflammatory cytokines IL-2 and IL-6 are associated with both the risk of developing depression, and with depression severity, although this relationship is modified by sex.

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Cellular immune phenotypes of depression: a gateway to precision medicine 

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In her debut blog, Fabiana Corsi-Zuelli summarises a recent systematic review and meta-analysis investigating the role of peripheral immune cells in depression, with a focus on implications for future immunotherapy trials.

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Biological pathways, antipsychotics and schizophrenia

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Murtada Alsaif summarises a small cohort study that uses shotgun mass spectrometry proteomic profiling to unravel the molecular pathways involved with antipsychotic response in people with schizophrenia.

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Biological markers for treatment response in first episode psychosis

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Stephen Wood summarises a systematic review of biological markers for treatment response in first episode psychosis, which discusses a number of hot topics in this field including inflammation, infectious disease and oxidative stress.

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