Marcus Munafo explores a recent study that uses genetic data and family environmental information to quantify the risk of chronic pain and the contribution of risk variants for major depressive disorder.
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Ian Jones summarises a number of studies that consider the benefits and harms of antidepressants during pregnancy, including a recent cohort study that found that exposure to antidepressants in the womb is associated with a modest increased risk of speech and language disorders.
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This World Mental Health Day, we share a Wellcome Trust interview with Professor Andrew McIntosh, who has a £4.7 million award to explore why people develop depression. He tells Wellcome how he hopes his work will improve the lives of people with mental health conditions, and how he looks after his own mental wellbeing.
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Ian Cummins reflects on a recent study looking at the relationship between fiscal austerity and suicide rates in Greece, Italy, Ireland, Portugal and Spain.
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This review compared direct digital sensors and indirect photostimulable phosphor plates for the detection of caries. Six studies were included in the review with 4 contributing to the meta-analysis. There was no significant difference between the two systems and they displayed good specificity and limited sensitivity.
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Ian Hamilton explores two recent articles that consider the shocking sex and gender inequities in addiction research.
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Leen Vereenooghe summarises the TOP-COG study (Towards Onset Prevention of COGnitive decline in adults with Down syndrome). This pilot RCT highlights the need to educate people with learning disabilities and their carers about the importance of research participation.
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Emily Stapley summarises a Mendelian randomisation study that investigates associations between the timing of menarche with depressive symptoms and depression in adolescence.
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Matt Field summarises a recent Swedish longitudinal cohort study of alcohol use disorder and mortality across the lifespan. This study quantifies the environmental and genetic risk factors that contribute to increased mortality in people with alcohol use disorder.
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André Tomlin summarises a 15 year observational study published today in The Lancet Psychiatry, which provides fascinating insight into suicide risk and absconding in psychiatric inpatient units with locked wards and open door policies.
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