Raphael Underwood presents a new Cochrane review of lithium for schizophrenia, which assesses the use of lithium as a monotherapy and also in combination with antipsychotics.
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Samei Huda summarises a small PET brain imaging study, which looks at two cohorts (Ultra High Risk of Psychosis v Controls and Schizophrenia v Controls) to compare relative levels of microglial activity.
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Murtada Alsaif summarises a small cohort study that uses shotgun mass spectrometry proteomic profiling to unravel the molecular pathways involved with antipsychotic response in people with schizophrenia.
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Andres Fonseca appraises a regression analysis looking at the quality and outcomes framework (QOF) and the impact it has on psychiatric admissions in people with severe mental illness.
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Samei Huda reviews a meta-analysis of multivariate pattern recognition studies, which aims to detect neuroimaging biomarkers for schizophrenia.
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Meg Fluharty considers the findings of a BMJ State of the Art review, which looks at the evidence for smoking cessation in people with chronic mental illness such as schizophrenia, unipolar depression, bipolar depression, anxiety disorders and PTSD.
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Can blood-based diagnostic panels help us reduce the misdiagnosis and inappropriate treatment often experienced by people with bipolar disorder? Murtada Alsaif reviews a recent retrospective study that has some encouraging findings for biologically identifying the disease.
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Sarah McDonald appraises the Better Sleep Trial (BEST), a pilot RCT which shows that CBT may be a promising treatment for insomnia in people with active psychotic symptoms.
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Alex Langford reflects on the media hype surrounding a new RCT of the NAVIGATE intervention; a comprehensive, multidisciplinary, team-based treatment approach for first episode psychosis.
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Tracey Roberts summarises a recent diagnostic test review, which suggests that early improvement can act as a predictor of later response to antipsychotics in schizophrenia.
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