Dementia in Down syndrome: Are we ready for a clinical trial?

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Leen Vereenooghe summarises the TOP-COG study (Towards Onset Prevention of COGnitive decline in adults with Down syndrome). This pilot RCT highlights the need to educate people with learning disabilities and their carers about the importance of research participation.

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Early menarche associated with depressive symptoms in early adolescence

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Emily Stapley summarises a Mendelian randomisation study that investigates associations between the timing of menarche with depressive symptoms and depression in adolescence.

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Associations between video game use, academic performance and mental health issues in European primary school children

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Pete Etchells posts his debut Mental Elf blog on a recent study, which explored whether video games were associated with mental illness, cognition or social skills in young children.

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Smokescreen: smoking in the movies and initiation of smoking in adolescents

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Sally Adams on a new systematic review and meta-analysis which suggests that smoking imagery in films may increase the risk of smoking initiation in young people.

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Cannabis and mental illness: it’s complicated!

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Suzi Gage considers the findings of a big new US cohort study, which investigates the relationship between cannabis use and various substance use, mood and anxiety disorders.

The blog also features a podcast interview with Suzi Gage talking about this new study and her own work in this field, plus a short conversation with Ian Hamilton highlighting his forthcoming #CannabisMatters event.

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Mondays and New Year’s Day associated with peaks in suicide incidence

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Emily Stapley reports on a recent study of the timing of general population and patient suicide in England. She discovers that Springtime, Mondays and New Year’s Day are all associated with peaks in suicide incidence.

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Proton-pump inhibitors and risk of dementia

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Caroline Struthers reports on a recent prospective cohort study which finds a strong association between the use of proton pump inhibitors and a significantly increased risk of dementia.

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What happens to people after discharge from secure psychiatric hospital?

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Laura Hemming considers a recent systematic review of patient outcomes following discharge from secure psychiatric hospitals. The review finds that patients from secure units have a higher chance of mortality and suicide following discharge, than people from other settings.

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Cannabis: what do we know and what do we need to know?

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Ian Hamilton considers a recent literature review published in JAMA Psychiatry, which explores the effects of cannabis use on human behaviour, Including cognition, motivation and psychosis.

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