Results: 632

For: Diagnosis

Long working hours are associated with increased alcohol use

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Sally Adams summarises a new BMJ systematic review and meta-analysis of working hours and alcohol use, which finds a link between longer working hours and risky alcohol consumption.

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Six out of ten GP surgeries are signed up to the Directed Enhanced Scheme in England, but 40% of patients with learning disabilities did not get a health check

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The Directed Enhanced Scheme offers reimbursement to GP surgeries to carry out annual health checks for people with learning disabilities. Here, we report on a cohort study which looked at the impact of the scheme over a three year period.

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Folic acid for depression: RCT finds no effect on reducing incidence of depression or bipolar

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Elly O’Brien summarises a recent RCT of folic acid for depression, which explores whether mood disorders can be prevented in young people at familial risk. The trial finds no evidence that folic acid supplementation reduces the incidence of mood disorders compared to those taking placebo.

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Alcohol use disorders and mortality in Nordic countries

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Andrew Jones appraises a recent study of mortality and life expectancy of people with alcohol use disorders in Denmark, Finland and Sweden, which provides some useful insight into the impact of hazardous alcohol use.

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Lifestyle changes for cognition and dementia: better than a new drug?

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Should all molecular research institutes looking at neurodegenerative diseases be replaced by parks, playgrounds and cycle paths? Mark Horowitz highlights a recent systematic review of modifiable risk factors associated with cognition and dementia, which suggests that from a public health perspective, there may be some sense in this idea.

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Risk factors for dementia: separating the facts from the myths

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We are grateful to Josephine Neale who has read the 104 page World Alzheimer Report 2014 and summarised it for us in this very readable blog. The report is a comprehensive analysis of the risk factors for dementia, which focuses on a range of protective and modifiable factors.

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Cannabis and mania: what’s the link?

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Kathryn Walsh summarises a systematic review which finds that cannabis use may exacerbate symptoms of mania in those with a diagnosis of bipolar disorder, and trigger symptoms of mania in the general population.

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Evidence to guide treatment of dementia in people with learning disability may be lacking, but new areas of research might help

As people with learning disabilities are living longer, then they are also experiencing age related disorders such as dementia, where they have been shown to have a higher risk than the general population. Here we look at a review of the current state of knowledge which looks at a range of issues, from prevalence, assessment, treatment and future directions for research.

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Bipolar disorder, suicide and criminality

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Elena Marcus summarises a double case-cohort study, which investigates the risk of suicide and criminal behaviours in people with bipolar disorder and their siblings, compared with the general population.

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Oral cancer detection: Limited evidence for use of chemiluminescence and autofluorescent imaging devices in primary care

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Early detection of oral cancer improves prognosis so methods to improve diagnosis are welcome. The review we look at today looks at two light-based systems: chemiluminescence or autofluorescence. 25 studies were included and they are well summarised but few were tested in primary care. Neither system provided much improvement on the level of sensitivity and specificity achieved by conventional oral examination. Therefore it is suggested that these tools are better suited to specialist clinics in which there is a higher prevalence of disease and where experienced clinicians may better discriminate between benign and malignant lesions.

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