Optical fluorescence imaging in oral cancer and potentially malignant disorders

leukoplakia

Manas Dave looks at a recent review of which considers the efficacy of optical fluorescence imaging as an adjunct to clinical oral examination for the detection of oral mucosal lesions. The review includes 27 studies and provides evidence to support additional high quality studies to assess its effectiveness.

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Human Papilloma Virus in oral potentially malignant disorders

Human Papilloma Virus

In this blog Manás Dave looks at a review of the prevalence of human papilloma virus (HPV) in oral potentially malignant disorders (OPMD). Although 52 studies were included one in five OPMDs being HPV positive is not a substantial link so teh findings need to be interpreted cautiously.

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Oral Proliferative Verrucous Leukoplakia: What are the clinical features?

Leukoplakia , Verrucous

Marianne Dobson in her first blog for the Dental Elf takes a look at a systematic review looking at the main clinical features of proliferative verrucous leukoplakia

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Oral lichen planus: How common is it worldwide?

Lichen Planus -histopathology

This review of the global prevalence of oral lichen planus (OLP) included 66 observational studies providing an estimate of prevalence of 1.01% (0.74 to 1.32%).

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Oral submucous fibrosis: Is treatment with hyaluronidase and corticosteroids effective?

A_close_up_of_Areca_nut

This review of the efficacy of hyaluronidase combined with corticosteroids in the management of oral submucous fibrosis (OSF)included 6 small RCTs of short duration. Only one of the RCTs was considered to be at low risk of bias so additional well conducted and reported studies with larger sample are needed to evaluate treatments for OSF.

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Oral leukoplakia: Malignant transformation rate

OLYMPUS DIGITAL CAMERA

This review of the rate of malignant transformation of oral leukoplakia included 34 many retrospective observational studies. The estimated mean malignant transformation rate was 9.7% (95%CI; 7.8% to 11.7%).

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Oral lichen planus: malignant transformation rate

Lichen_planusWickham's

This review of the malignant transformation rate of oral lichen planus and associated risk factors included 33 studies. Using a strict definition the authors found a malignant transformation rate of 0.44%.

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Top Dental Elf Blogs: May – Aug 2018

The elves have been mining the archive for research blogs to support CQC's recommendations on high-quality adult social care services and support.

Popular Dental Elf blogs in May-Jun 2018 include; tooth whitening; oral surgery and anticoagulants, anxiety management in children using CBT and oral lichen planus

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Aloe vera for treatment of oral submucous fibrosis?

shutterstock_32414035 - Betel leaf

This review effectiveness of aloe vera on alleviating the symptoms of oral submucous fibrosis included 6 RCTs . The findings suggest a possible benefit but 5 of the trials were at high risk of bias so the findings should be viewed cautiously.

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Oral lichen planus: Rate of malignant transformation

Lichen_planusWickham's

This review of the malignant transformation rate (TR) of oral lichen planus included 21 observational studies the majority of which were retrospective. The overall estimate of TR was 1.4%.

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