This review of the effectiveness of sodium bicarbonate in the prevention and management of oral mucositis included 11 RCTs. The included studies were small, hetrogeneous and suggested little benefit from the use of sodium bicoarbonate mouthwashes.
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This review of the effect of additives incorporated into lidocaine solution on the success of inferior alveolar nerve block (IANB) included 12 RCTs. The findings suggest that additives did not improve the success rate of IANB but the evidence is of low to very low certainty.
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This review of the effect of baking soda toothpastes on plaque and gingivitis included 21 studies providing 43 comparisons that suggest some benefit with respect to plaque removal.
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14 RCTs were included in this review of the effect of buffering local anaesthetics in reducing infiltration pain and anaesthesia onset time in dentistry. While slight reductions in onset time was seen in inflamed tissues and for IAN block these were not considered to be clinically significant. However the overall quality of the evidence was low.
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25 studies were included in this review of denture hygiene practices. Mechanical interventions in conjunction with chemical agents were the most effective, Denture brushing was the most common patient practice.
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