John Baker summarises a review of commonly prescribed medication that covers seven psychiatric drugs, including antidepressants, antipsychotics, benzodiazepines, amphetamines, methylphenidate and cholinesterase inhibitors.
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John Baker summarises a recent Cochrane systematic review of psychosocial interventions for benzodiazepine harmful use, abuse or dependence.
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Andrew Shepherd appraises and summarises a systematic review of antidepressant withdrawal symptoms after SSRI discontinuation, which leads him to reconsider his own clinical practice.
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Amy Green appraises a systematic review of CBT for insomnia (CBTi) in people with comorbid mental illness, which concludes that cognitive behaviour therapy could be an effective alternative to hypnotics. However, concerns about the review methodology cast some doubt on the findings.
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Liz Hughes summarises two recent studies (1 systematic review and 1 RCT) that both investigate brief interventions for reducing the use of benzodiazepines in primary care.
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Laurence Palfreyman highlights a recent BMJ study, which finds an association between Alzheimer’s disease and benzodiazepine use.
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Benzodiazepines are used to treat insomnia, anxiety and chronic back pain due to their sedative and muscle relaxing effects. They’ve got a sting in the tail though and can cause memory disruption, loss of coordination and dependence if used long term. It’s therefore recommended that other treatments, such as psychological interventions, are tried first and [read the full story…]
The potential dangers of illegal drug use are never far from the media spotlight, and drug use during pregnancy may be associated with particular health problems both for the Mother and baby. Drug use during pregnancy has been linked with a number of negative outcomes, for example, cocaine use has been linked with an increased [read the full story…]
Benzodiazepines are an effective treatment for acute anxiety and transient insomnia, but guidelines advise that they should not be prescribed for longer than a few weeks as their long-term use can lead to dependency and falls in older people (amongst other things). The evidence appears compelling and yet benzodiazepines are still widely prescribed in the [read the full story…]
Polypharmacy is the simultaneous use of two or more drugs to treat a single health condition. Polypharmacy is often used in the treatment of schizophrenia where people are regularly prescribed two or more antipsychotics, as well as antidepressants and/or benzodiazepines, although there is little evidence to prove that these combinations are more effective than monotherapy. [read the full story…]
