Results: 32

For: cancer

Osteoradionecrosis of the jaws: Prevention in adult patients with head and neck cancer

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This Cochrane review of interventions for preventing osteoradionecrosis of the jaws in adults with head and neck cancer undergoing curative or adjuvant (i.e. non-palliative) radiotherapy included 4 RCTs. The limited quality of the available studies means evidence regarding the interventions evaluated in this review is uncertain.

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Toombak: A risk factor for oral leukoplakia and cancer

29 September 2013. El Fasher: A trader shows a tray with tombac (chewing tobacco) at the market in El Fasher, North Darfur. Tombac is one of North Darfur’s major cash crops. The traditional markets for tombac include South Sudan, Blue Nile and South Kordofan states. Farmers assure four million people in Darfur are dependent on the cultivation and sale of tobacco. They claim that tobacco had been produced in the region since 1850.  Originally, the production of tombac started in Tombouctou (Mali) and later it was imported to Egypt and Darfur.  Photo by Albert González Farran, UNAMID

This review of the association between toombak use and oral leukoplakia and oral squamous cell carcinoma included 8 observational studies suggesting a strong association.

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Oral mucositis in cancer patients: the effect of oral supplementation

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This review of of the effects of oral supplementation on the prevention and/or treatment of oral mucositis in patients with cancer undergoing chemotherapy and/or radiotherapy included 12 RCTs and suggest that Zinc supplements may be beneficial.

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Dental visits and head and neck cancer

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This review of a link between past dental visits/check-ups and the incidence cancers of head and neck includes 38 studies the majority of which are case-controlled studies. The findings suggest that those are irregular of never attenders are more likely to have head and neck cancer.

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Oral Cancer: Elective or therapeutic neck dissection?

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This review of neck dissection (END) in patients with squamous cell carcinoma (SCC) of the oral cavity and clinically N0 neck included 6 studies suggesting fewer recurrences with END, but the evidence of very low quality.

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Mucositis in adult cancer patients reduced with keratinocyte growth factor

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This Cochrane review of cytokines and growth factors for preventing oral mucositis in patients having cancer treatment included 35 RCTs finding keratinocyte growth factor beneficial in the prevention of oral mucositis .

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Drugs to prevent salivary gland damage following radiotherapy to the head and neck

This Cochrane review of drugs for the prevention of radiation-induced salivary gland dysfunction included 39 studies, while a range of agents was tested the evidence found is not sufficient to highlight much promise in terms of effective preventative treatments.

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Oral mucositis in cancer patients: no benefit from chlorhexidine mouthwash

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This review of chlorhexidine (CHX) for prevention & treatment of oral mucositis included 12 RCTs with 9 contribution to the meta-analysis. CHX was not significantly effective in preventing mucositis or reducing its severity.

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Oral Mucositis: can honey reduce its severity?

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This review of the use of honey to educe the severity of radio/chemotherapy-induced oral mucositis identified 7 low quality RCTs that suggest that use of honey may reduce the severity of oral mucositis.

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