Results: 34

For: cancer

Oral mucositis in cancer patients: no benefit from chlorhexidine mouthwash

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This review of chlorhexidine (CHX) for prevention & treatment of oral mucositis included 12 RCTs with 9 contribution to the meta-analysis. CHX was not significantly effective in preventing mucositis or reducing its severity.

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Oral Mucositis: can honey reduce its severity?

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This review of the use of honey to educe the severity of radio/chemotherapy-induced oral mucositis identified 7 low quality RCTs that suggest that use of honey may reduce the severity of oral mucositis.

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Does recession = poorer health? Evidence strongest for suicide and mental illness

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Claire Niedzwiedz examines a recent systematic review which looks at the possible harm caused by the 2008 financial crisis and recession on the health of people living across Europe.

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Dental Implants: survival rate in irradiated patients

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40 studies were identified for this review of dental implants in irradiated patients. While survival rates were good, they were lower than in non-irradiated areas. As the majority of the included studies were retrospective the findings should be viewed cautiously.

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Marijuana use and head and neck cancer risk #CannabisMatters

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9 case-controlled studies were included in this review of the effect of marijuana use on head and neck cancer. The findings suggest no association marijuana use and head and neck cancer but other reviews suggest that this may differ by tumour site

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Smoking cessation interventions for head and neck cancer patients

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This review of smoking cessation for patients with head and neck cancer included 8 studies ( 3 RCTs) and suggests that those receiving counseling had a 26% higher quit rate than with controls

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High frequency or prolonged use of mouthwash increased risk of head and neck cancer

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This study from the INHANCE collaboration pooled data from 12 case-controlled studies. Long-term use (35 yrs) of mouthwash was associated with an increase risk OR=1.15 (95%CI; 1.01 to 1.30) of head and neck cancer but with regular (>2 x daily), long-term (>35 years) use OR = 1.75 (95%CI; 1.25 to 2.48).

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Coffee consumption and oral cancer

Prescribing a placebo does not equate to no treatment, because the healthcare setting itself should include all kinds of supportive and therapeutic elements.

This review includes 11 case-controlled and 4 cohort studies and suggests a 37% reduction of oral cancer risk in high coffee drinkers compared with low or no coffee drinkers OR= 0.63 (95%CI; 0.52 – 0.75)

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Tobacco use and alcohol intake key risk factors for head and neck cancer

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The International Head and Neck Cancer Epidemiology (INHANCE) consortium is a collaboration of research groups leading large epidemiology studies to improve the understanding of the causes and mechanisms of head and neck cancer. This overview paper provides a summary their findings over the past decade.

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Oral cryotherapy reduces oral mucositis in patients receiving 5FU-based treatment for solid cancers

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This Cochrane review looked at cryotherapy (ice chips) for preventing oral mucositis in patients with cancer. 14 RCTS involving 1280 patients were included providing evidence that oral cryotherapy leads to large reductions in oral mucositis of all severities in adults receiving 5FU for solid cancers. However there was less confidence confident in the ability of oral cryotherapy to reduce oral mucositis in adults receiving high-dose melphalan before haematopoietic stem cell transplantation (HSCT).

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