Earlier this year the US Surgeon General recommend that tobacco cessation counselling and pharmacotherapy should be offered to smokers in every healthcare setting (US Department of Health and Human Services, 2014).
Hospitalisation presents an excellent opportunity for smoking cessation. However, research suggests that hospital-delivered interventions are only successful if treatment is extended beyond hospital discharge (Rigotti et al, 2012).
Establishing how to sustain tobacco cessation after discharge is a major challenge facing hospitals. The present study (Rigotti et al, 2014) aimed to address this limitation by determining the effectiveness of an evidence-based sustained care intervention of both tobacco cessation counselling and medication on smoking cessation after hospital discharge. The authors hypothesised that sustained care would increase the number of individuals who used the cessation intervention and the number of individuals who were tobacco abstinent at 6 months post-discharge.
Participants and recruitment
- Smokers (smoked ≥1 cigarette/day during the month before admission)
- Aged 18 years and above
- Individuals who received smoking cessation counselling whilst in hospital
- Smokers who intended to quit following discharge and agreed to take smoking cessation medication
Exclusion criteria included:
- Individuals who had a hospital stay of less than 24 hours
- Substance use in last 12 months other than alcohol, tobacco and marijuana
- Admission for a drug overdose
- Individuals who could not give informed consent
- Individuals admitted to the obstetric or psychiatric units
- Individuals who had life expectancy of less than 12 months or were medically unstable
Recruitment of hospitalised smokers was achieved via electronic registration of patient smoking status at admission. The tobacco treatment service accessed records daily and screened smokers for study inclusion. Participants were randomised to treatment group, which was stratified by cigarette use per day (<10 or ≥10).
Sustained Care Intervention
The sustained care intervention included two components:
- A free 30-day supply of a tobacco cessation medication of choice (refillable for up to 90 days)
- 5 automated interactive voice response telephone calls (at 2, 14, 30, 60 and 90 days post-discharge)
The telephone calls offered cessation support and encouraged medication use and adherence. Participants could request to receive a call-back from a counsellor if they were feeling unconfident about abstinence, had questions about medication or had relapsed to smoking. The standard care intervention provided smokers with a recommendation for a cessation medication and a telephone number for a free-call quit line.
Baseline measures included:
- Demographics (e.g. age, sex)
- Health insurance status
- Smoking history
- Nicotine dependence
- Prior use of cessation treatment
- Presence of a smoker at home
- Importance of and confidence in quitting
- Alcohol use
Hospital record gave information regarding:
- Length of hospital stay
- Diagnosis at discharge
- Recommended cessation medication
Participants were contacted at 1, 3 and 6 months post-discharge to collect data on tobacco use and tobacco cessation treatment use (counselling or pharmacotherapy).
The primary outcome of abstinence at 6 months was verified by a salivary cotinine sample ≤10 ng/ml (a metabolite of nicotine). Participants using NRT had an in-person verification of exhaled carbon monoxide <9 ppm. Secondary outcomes of self-reported 7-day point prevalence and continuous abstinence were measured at 1, 3 and 6 months post-discharge.
Recruitment and Retention
1,757 inpatients met initial study inclusion criteria. Of these 904 (50%) completed screening for eligibility, 432 (48%) were eligible and 397 patients were consented and randomised to either sustained care (n = 198) or standard care (n =199).
- Had an average age of 53
- 48% were male
- 81% were non-Hispanic whites
- 51% had a high school education
- Smoked an average of 16.7 cigarettes per day
- Had an average hospital stay of 5 days
- 45% had a primary discharge diagnosis that was smoking-related
Tobacco cessation treatment in hospital did not differ between intervention groups.
Use of Tobacco Cessation after Discharge
- Participants in the sustained care group were more likely to use cessation treatment during the month after discharge compared to those in the standard care group (83% vs 63%, respectively; relative risk [RR], 1.32 [95% CI, 1.16 to 1.49]; P < .001)
- This was the case for:
- Pharmacotherapy (79% vs 59%; RR, 1.34 [95% CI, 1.17 to 1.54]; P < .001) and
- Counselling (37% vs 23%; RR, 1.63 [95% CI, 1.19 to 2.23]; P = .002)
- A greater number of participants in the sustained care group achieved the primary outcome of biochemically verified past 7-day abstinence at 6 month follow-up compared to those in the standard care group (26% vs 15%, respectively, RR, 1.71 [95% CI, 1.14-2.56]; risk difference, 11% [95% CI, 3%-19%]; P = .009).
- Self-reported abstinence rates were higher for the sustained care group, compared with the standard care group for both point-prevalence abstinence (past 7-days) and continuous abstinence:
- 7-day self-reported abstinence rates were 52% for sustained care and 39% for standard care at 1 month (RR, 1.33 [95% CI, 1.07 to 1.65]; P = .01)
- At 6 months, rates were 41% vs 28% respectively (RR, 1.45 [95% CI, 1.10 to 1.92]; P = .008).
- Self-reported continuous tobacco abstinence was greater in the sustained care group, compared to standard care at every follow-up assessment:
- 1 month (46% vs 33%, respectively; RR, 1.39 [95% CI, 1.08 to 1.78]; P = .01)
- 3 months (34% vs 24%; RR, 1.43 [95% CI, 1.04 to 1.97]; P = .03)
- 6 months (27% vs 16%; RR, 1.70 [95% CI, 1.15 to 2.51]; P = .007).
The proposed sustained care intervention indicates the potential of an effective, low-cost intervention for tobacco cessation following initial abstinence in a hospital setting.
The intervention addresses the challenge of individuals who may get “lost in the system” by offering a novel method for bridging the gap between inpatient and outpatient care. Additionally, the cost per quit analysis suggests that the sustained care intervention also has the potential to be cost effective across a range of smokers.
The following points should be considered in the interpretation of these findings.
- The sustained care intervention reflects combination pharmacotherapy and counselling. It is not possible to determine the individual contribution of the free medication and the voice response support call components of treatment on post-discharge cessation.
- The study only includes participants who intended to quit smoking post-discharge. It is not known how a sustained care intervention may work for smokers who are not motivated to quit.
Rigotti et al. (2014) Sustained care intervention and postdischarge smoking cessation among hospitalized adults: a randomized clinical trial. JAMA. 2014 Aug 20;312(7):719-28. doi: 10.1001/jama.2014.9237. [PubMed abstract]
US Department of Health and Human Services (2014) The health consequences of smoking-50 years of progress: a report of the surgeon general. http://www.surgeongeneral.gov/library/reports/50-years-of-progress/full-report.pdfx
Rigotti NA, Clair C, Munafò MR, Stead LF. (2012) Interventions for smoking cessation in hospitalised patients. Cochrane Database of Systematic Reviews 2012, Issue 5. Art. No.: CD001837. DOI: 10.1002/14651858.CD001837.pub3.
RT @Mental_Elf: Sustained smoking cessation intervention for hospitalised smokers http://t.co/wH56Oh6qoW
Sustained smoking cessation intervention for hospitalised smokers: Earlier this year the US Surgeon General re… http://t.co/DGs7veGJ5g
“@Mental_Elf: Sustained smoking cessation intervention for hospitalised smokers http://t.co/VnRIxQUhVY” @ShellyMun @OntarioShores
Today @SallyScientist on @JAMA_current RCT of sustained care intervention for hospitalised smokers http://t.co/r03hxa2tXS
Sustained smoking cessation intervention for hopitalised smokers: #mentalhealth patients were excluded from the study http://t.co/O2JGFq5YXQ
Can sustained care extend the effects of smoking cessation in hospital? I blogged for @Mental_Elf here http://t.co/63gSBZDCZa
Sustained smoking cessation for hospitalised smokers http://t.co/mvRamNOXZL
How can we help people in hospital quit smoking? http://t.co/r03hxa2tXS
@Mental_Elf Don’t let them go outside. Simples. That’s the method employed on locked psychiatric wards & it’s so effective. Um.
@Mental_Elf this very topic has been under discussion today at #uksbm14 @UKSBM no answers for you though!
@drabagnall @UKSBM @Mental_Elf Vital reading: http://t.co/7uKEz6D3DV & http://t.co/db9diBwAG9 consider -ve MH fx of denying people choice.
“@Mental_Elf: How can we help people in hospital quit smoking? http://t.co/7xkVtXqFRD” see #uksbm14 for tweets on Britton keynote on this
Mental Elf: Sustained smoking cessation intervention for hospitalised smokers http://t.co/so4Trna3De
Tweeps at #uksbm14 may like to read @SallyScientist’s blog on sustained smoking cessation for hospitalised smokers http://t.co/r03hxa2tXS
@Mental_Elf Smoking cessation for SOME hospitalised smokers: psychiatric patients were excluded. Do you know why? #uksbm14 @SallyScientist
@Mental_Elf Still trying to find any studies on long-term effectiveness of banning detained patients from smoking. #uksbm14 @SallyScientist
@sectioned_ @mental_elf @sallyscientist Do you mean in terms of effectiveness of smoking cessation or impact on MH (or both)?
Sustained #smoking cessation for hospitalised smokers http://t.co/m6HzhiX4Fx via @Mental_Elf cc @cbcwhitecoat
Princess Sunshyne liked this on Facebook.
RCT of sustained care intervention (counselling & medication) to help hospitalised smokers quit and stay quit http://t.co/r03hxa2tXS
Sustained smoking cessation intervention for hospitalised smokers http://t.co/bZUXbIfrEF via @feedly
Don’t miss: Sustained smoking cessation intervention for hospitalised smokers http://t.co/r03hxa2tXS
June Dunnett liked this on Facebook.
Sustained #smokingcessation intervention for hospitalised #smokers http://t.co/zH9R17H8If Review of the evidence from @Mental_Elf #hospitals
I presume this is physical acute hospitals? Would be interesting to discuss about the links of this to the Smoke Free initiative which is happening in many trusts, and the ethics of this with people who are in hospital against their will (under Mental Health Act).
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