Parents and caregivers of people with Williams syndrome rate benefits from medications in reducing anxiety

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Williams syndrome is a neuro-developmental genetic disorder caused by gene deletion estimated to have a prevalence of 1 in 7,500 to 1 in 20,000 live births. Previous studies have identified anxiety as part of the behavioural phenotype of the syndrome The authors of this US study set out to look at the effectiveness and adverse [read the full story…]

Individual CBT, with or without family CBT, could be the best first line treatment for people at high risk of schizophrenia

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Schizophrenia is a debilitating illness that affects an estimated 25 million people worldwide. People with the condition can experience a huge amount of disability (both social, physical and psychological), but we know that early intervention can help reduce the duration of the illness and prevent further episodes of relapse. People with schizophrenia usually experience a [read the full story…]

NICE publish first guideline for psychosis and schizophrenia in children and young people

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Everyone who read the extracts from Michael Schofield’s memoir, published by the Guardian on January 19th, must surely have been moved by the sometimes harrowing description of his daughter Janni who was diagnosed with child-onset schizophrenia aged just 7 years old. Janni is an exception, as schizophrenia generally starts between the ages of 15 and [read the full story…]

NICE publish new evidence summary on psychosis with coexisting substance misuse

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The NICE guideline on psychosis with coexisting substance misuse was published in 2011, which means it’s now nearly 3 years out of date. This is because guidelines take many months to produce, so by the time they are published the evidence in them is 1 year old at best. Some NICE guidelines are supplemented by [read the full story…]

Check out the new BITE-sized mental health summaries from the NIHR CLAHRCs

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Anyone who’s spent any time at all on the Mental Elf website, or any of the other National Elf Service sites, knows that we elves love succinct and focused summaries that are easy to read and quick to digest. It’s always a delight to see other groups publishing similar resources, so I’ve decided today to [read the full story…]

Antipsychotics don’t help increase weight or reduce symptoms for women with anorexia nervosa

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Evidence-based treatments for mental health conditions have come on in leaps and bounds in the last 20 years. I remember as a young elf, skipping around the country and running workshops on evidence-based mental health; training psychiatrists, psychologists, nurses and others. There wasn’t much gold standard evidence to choose from back then and there was [read the full story…]

Learning disability support workers call for more information on side effects of psychotropic medications

Antipsychotic overprescribing is common in people with learning disabilities who have no record of severe mental illness.

Studies have suggested that anti-psychotic medications comprise between 30–50% of all psychotropics prescribed for people with learning disabilities, often prescribed for people with challenging behaviours with no diagnosis of mental illness. Reviews of their use have suggested however that there is no strong evidence supporting the anti-aggressive properties of anti-psychotics. This study in Australia was [read the full story…]

Non-pharmacological interventions can help prevent and reduce weight gain in people who take antipsychotics

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The reduced life expectancy (15-20 years less) often faced by many people with schizophrenia is frequently a result of cardiovascular disease. Lifestyle choices (smoking, lack of exercise and poor diet) can increase the risk of these diseases, but people who take antipsychotic drugs often have the additional problem of weight gain that is caused by [read the full story…]

Cochrane review suggests adding promethazine to haloperidol to rapidly tranquillise psychotic patients with fewer side effects

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The hallucinations and delusions associated with psychosis can be frightening and may sometimes result in aggressive or violent behaviour. Of course, this can be incredibly challenging for the patient, but it can also be a real test for mental health staff who have to try and minimise the harm that patients do to themselves and others. Haloperidol [read the full story…]

NICE publish evidence update on generalised anxiety disorder in adults

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NHS Evidence have published an evidence update on generalised anxiety disorder in adults. Evidence updates are summaries of selected high quality evidence that has appeared since the relevant guideline was published, in this case NICE clinical guideline 113 ‘Generalised anxiety disorder and panic disorder (with or without agoraphobia) in adults: management in primary, secondary and community care’ [read the full story…]