Tooth grinding in children and adolescents with neurodevelopmental disorders


This review of the prevalence of tooth grinding and/or clenching in children and adolescents with neurodevelopmental disorders and other developmental anomalies included 77 studies from 2 countries. However a large proportion of the studies were at high risk of bias so the findings need to be interpreted with caution.

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Social approachability behaviour of adults with Williams syndrome tested in observational study

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Adults with Williams syndrome are said to have a highly social personality, but can find it difficult to form and maintain relationships.

Here we report on a recent observational study which compared parent and self-report measures of social behaviour to observations of real life social situations.

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Parents and caregivers of people with Williams syndrome rate benefits from medications in reducing anxiety


Williams syndrome is a neuro-developmental genetic disorder caused by gene deletion estimated to have a prevalence of 1 in 7,500 to 1 in 20,000 live births. Previous studies have identified anxiety as part of the behavioural phenotype of the syndrome The authors of this US study set out to look at the effectiveness and adverse [read the full story…]

Further evidence suggests anxiety is part of behavioural phenotype of Williams syndrome


Williams syndrome is genetic condition caused by gene deletion and is estimated to have a prevalence of 1 in 7,500 to 1 in 20,000 live births. Previous studies, which have relied mainly on the testimony of parents and carers, have suggested that people with Williams syndrome may have a disposition towards anxiety. The authors of [read the full story…]

Extreme sensitivity to sound mediates pathways for language development in Williams syndrome


Hyperacusis is an extreme sensitivity to sound, which may have a psychological or organic basis. People with Williams Syndrome, a neurodevelopmental disorder, often have this sensitivity to noise. The researchers in this study looked at the extent to which such sensitivity might interfere with perception of speech in children and adults with the syndrome. All [read the full story…]