This review of the efficacy of different anti-plaque chemical agents in managing gingivitis included 32 RCTS of toothpastes and 19 of mouthrinses suggested greater benefits with some agents.
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63 RCTs contributed to this network meta-analysis of the effectiveness of anti-plaque agents. Results suggested that toothpastes containing triclosan-copolymer or chlorhexidine and mouthrinses containing essential oils or chlorhexidine had the most effect on plaque indicies at 6 months.
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This review of essential oils mouthwashes included 16 RCTs and found them to be more effective for the reduction of plaque and gingival inflammation than mechanical plaque control either alone (placebo) or in combination with mouthwashes with CPC.
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