Direct pulp capping in primary teeth

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This review of direct pulp capping in vital primary teeth included 12 RCTs testing 16 different pulp capping agents. Interpretation of the available data is limited as few trials comparign the same agents and the quality of the trials is low.

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Alveolar ridge preservation: which grafting material?

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This review of grafting materials for alveolar ridge preservation included 38 small RCTs. 34 different materials were investigated with the findings suggesting that no grafting material increased new bone formation between 3 and 6 months after tooth extraction.

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Periodontal infrabony defects: does autologous platelet concentrates (APC) improve surgical outcomes

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38 RCTs were included in this Cochrane review of the effects of autologous platelet concentrates (APC) used as an adjunct to periodontal surgery. Very low quality evidence was found for two approaches involving open flap debridement.

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Gingival recession: which surgical treatment technique?

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This Cochrane review of the efficacy of different root coverage procedures for gingival recession included 48 RCTs describing a range of procedures. Most procedures led to a reduction in gingival recession.

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Intrabony periodontal defects – does combining bone substitutes and enamel matrix derivatives improve outcomes?

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This review of combining bone substitutes and enamel matrix derivatives for the management of intrabony periodontal defects only identified 5 small RCTs of limited quality. The addition of EMD to bony substitutes was not seen to be beneficial but the results should be interpreted cautiously due to limitations in the available evidence.

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Periodontal regeneration therapies: Are benefits long-term?

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This review of periodontal regeneration therapies included 52 trials. While the results suggest some statistically significant improvements they may not be clinically important. There is also limited data for outcomes longer than 12 months.

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Lasers for surgical periodontal treatment – insufficient evidence of effectiveness

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Eight small trials were identified for this review of lasers as an adjunct to surgical periodontal treatment. The limited number of studies and variation in the types of lasers used means there is insufficient evidence to support their effectiveness.

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Gingival recession: root surface modifiers did not improve surgical outcomes

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Six small randomised controlled trials were found for this review assessing the use of root surface modifiers to improve the outcome of gingival recession surgery. None of the agents evaluated were seen to be of benefit.

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Review suggests small benefits from enamel matrix derivative in the treatment of periodontal pockets of suprabony defects

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A number of different regenerative techniques, guided tissue regeneration (GTR), bone grafting (BG) and the use of enamel matrix derivative (EMD) have been used to try and regenerate periodontal tissues. The aim of this review was to assess the effectiveness of EMD in the treatment of periodontal pockets of suprabony defects. Searches were conducted in [read the full story…]

Combination therapies performed better than single ones for treating periodontal bony defects, but additional benefits were small

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A range of regenerative treatments have been used for the  treatment of periodontal infrabony defects. Guided tissue regeneration (GTR) and enamel matrix derivatives (EMD) are two popular treatment and they have both been used in combination with other treatment.   This network meta-analysis was conducted to assess the potential effects of the various combinations. Unlike a [read the full story…]